Open Access Highly Accessed Research article

Plasma and synovial fluid microRNAs as potential biomarkers of rheumatoid arthritis and osteoarthritis

Koichi Murata, Hiroyuki Yoshitomi*, Shimei Tanida, Masahiro Ishikawa, Kohei Nishitani, Hiromu Ito and Takashi Nakamura

Author Affiliations

Department of Orthopaedic Surgery, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shogoin, Sakyo, Kyoto 606-8507, Japan

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Arthritis Research & Therapy 2010, 12:R86  doi:10.1186/ar3013

Published: 14 May 2010

Additional files

Additional file 1:

Supplementary Figure S1. Correlation between plasma miRNA and synovial fluid miRNA. There were no correlations between plasma miRNA concentrations and synovial fluid miRNA concentrations of patients with RA (A) or OA (B), except miR-223 from OA patients.

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Additional file 2:

Supplementary Figure S2. Comparison of SF/PB ratio of miRNA between RA and OA. Significant differences between RA and OA are indicated by * = P < 0.05, ** = P < 0.01.

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