Table 5 |
|||||
|
Sensitivity analysis for the effect size on pain at post treatment |
|||||
|
Outcome title |
Number of study arms |
Number of patients on aerobic exercise |
Effect sizea |
Test for overall effect, P value |
Heterogeneity, I2; τ2 (%) |
|
|
|||||
|
Adequate sequence generation |
|||||
|
Adequate |
11 |
251 |
-0.20 (-0.38, -0.01) |
0.04 |
0; 0 |
|
Unclear or nonadequate |
18 |
348 |
-0.39 (-0.61, -0.18) |
0.0004 |
39; 0.07 |
|
Allocation concealment |
|||||
|
Adequate |
8 |
223 |
-0.24 (-0.47, -0.01) |
0.04 |
24; 0.02 |
|
Unclear or nonadequate |
19 |
344 |
-0.35 (-0.54, -0.16) |
0.0002 |
28; 0.04 |
|
Blinding of assessor |
|||||
|
Yes |
12 |
306 |
-0.20 (-0.36,-0.03) |
0.02 |
0; 0 |
|
No or unclear |
15 |
261 |
-0.41 (-0.66,-0.16) |
0.001 |
38;0.08 |
|
ITT analysis |
|||||
|
Yes |
13 |
315 |
-0.22 (-0.39, -0.06) |
0.009 |
0; 0 |
|
No |
14 |
252 |
-0.39 (-0.62, -0.16) |
0.001 |
36; 0 |
|
Adequacy of outcomes for meta-analysis |
|||||
|
Yes (means) |
24 |
517 |
-0.35 (-0.51,-0.19) |
<0.0001 |
28;0.04 |
|
No (medians) |
3 |
43 |
-0.05 {-0.43,-0.32) |
0.78 |
0; 0 |
|
Sample size |
|||||
|
<25 |
3 |
30 |
-0.33 (-1.00,0.33) |
0.33 |
34; 0.12 |
|
25 to 50 |
15 |
188 |
-0.41 (-0.70,-0.13) |
0.005 |
46;0.11 |
|
>50 |
9 |
349 |
-0.23 (-0.39,-0.08) |
0.004 |
0; 0 |
|
Patients with mental disorders included |
|||||
|
Yes |
16 |
312 |
-0.43 (-0.78, -0.08) |
0.02 |
73; 0.28 |
|
No or unclear |
14 |
315 |
-0.40 (-0.61, -0.19) |
0.0002 |
38; 0.05 |
|
|
|||||
|
ITT, intention to treat. aStandardised mean difference (95% confidence interval). |
|||||
|
Häuser et al. Arthritis Research & Therapy 2010 12:R79 doi:10.1186/ar3002 |
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