Table 4 |
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|
Subgroup analysis for the effect size on pain at post treatment |
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|
Outcome title |
Number of study arms |
Number of patients on AE |
Effect sizea |
Test for overall effect, P value |
Heterogeneity, I2; τ2 (%) |
|
|
|||||
|
Type of exercise |
|||||
|
Land-based |
22 |
463 |
-0.29 (-0.46,-0.13) |
0.0005 |
27; 0.03 |
|
Water-based |
3 |
61 |
-0.67 (-1.04,-0.29) |
0.0005 |
0; 0 |
|
Mixed |
4 |
43 |
-0.03 (-0.45,0.39) |
0.89 |
0; 0 |
|
Type of exercise |
|||||
|
AE only |
12 |
273 |
-0.35 (-0.61,-0.09) |
0.0008 |
48; 0.09 |
|
AE combined with other exercise |
17 |
294 |
-0.28 (-0.45,-0.15) |
0.001 |
0; 0 |
|
Duration of study |
|||||
|
<7 weeks |
2 |
32 |
-1.16 (-1.86,-0.48) |
0.001 |
36; 0.09 |
|
7 to 12 weeks |
13 |
194 |
-0.24 (-0.50,-0.02) |
0.03 |
16; 0.02 |
|
>12 weeks |
12 |
338 |
-0.24 (-0.40,-0.08) |
0.004 |
0; 0 |
|
Frequency of training/week |
|||||
|
1 time/week |
2 |
37 |
-0.07 (-0.54,03.9) |
0.48 |
Not applicable |
|
2 times/week |
5 |
127 |
-0.69 (-0.95,-0.27) |
0.0004 |
35; 0.06 |
|
3 times/week |
16 |
241 |
-0.35 (-0.62,-0.09) |
0.009 |
48; 0.10 |
|
>3 times/week |
4 |
142 |
-0.13 (-0.38, 0.13) |
0.33 |
2; 0 |
|
Total duration aerobic exerciseb |
|||||
|
<1,000 minutes |
10 |
175 |
-0.47 (-0.86,-0.08) |
0.02 |
62; 0.19 |
|
1,000 to 2,000 minutes |
9 |
175 |
-0.36 (-0.59,-0.13) |
0.002 |
0; 0 |
|
>2,000 minutes |
8 |
217 |
-0.15 (-0.34, 0.05) |
0.15 |
0; 0 |
|
Intensity of AEc |
|||||
|
<50% maxHR |
1 |
37 |
-0.09 (-0.54, 0.36) |
Not applicable |
Not applicable |
|
Left up to patient |
2 |
79 |
-0.42 (-0.77, -0.07) |
0.02 |
0; 0 |
|
> 50% maxHR |
21 |
367 |
-0.26 (-0.42,-0.11) |
0.0007 |
0; 0 |
|
Type of control group |
|||||
|
Attention placebo |
7 |
229 |
-0.27 (-0.62, 0.07) |
0.12 |
67; 0.12 |
|
Therapy as usual |
10 |
147 |
-0.47 (-0.71,-0.24) |
<0.0001 |
0; 0 |
|
Active therapy |
10 |
191 |
-0.27 (-0.49,-0.06) |
0.01 |
0; 0 |
|
|
|||||
|
AE, aerobic exercise; maxHR, maximum of age-adjusted maximum heart rate. aStandardised mean difference (95% confidence interval). bIf no precise duration of AE was given, 50% of the total exercise time was assumed for aerobic exercise. cStudies that did not report the intensity of training were excluded from analysis. |
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|
Häuser et al. Arthritis Research & Therapy 2010 12:R79 doi:10.1186/ar3002 |
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