Table 4

FMD, NMD and IMT in MCTD patients with/without cardiovascular disease and controls

%FMDa

P value

%NMDa

P value

IMTa

P value


Age at investigation (years)

-0.0221

0.878

-0.6700

0.001

0.5468

0.001

Disease duration (years)

-0.6468

0.001

-0.1314

0.3628

0.1968

0.1706

Systolic blood pressure (mmHg)

-0.5423

0.001

-0.1094

0.4492

0.2220

0.1211

Diastolic blood pressure (mmHg)

0.0946

0.5133

0.1005

0.4872

-0.1597

0.2676

Serum triglycerides (mmol/l)

-0.3396

0.0158

0.2165

0.1309

-0.0411

0.7765

Serum cholesterol

-0.0459

0.7514

0.0508

0.7255

-0.0209

0.8851

Apolipoprotein A1 (g/l)

0.6203

0.001

-0.0805

0.5782

-0.0248

0.8640

Apolipoprotein B (g/l)

-0.3102

0.061

-0.0891

0.5997

0.0767

0.6517

Paraoxonase-1 activity

0.5957

0.001

0.1317

0.3619

-0.2789

0.0497

hs-CRP

-0.4057

0.003

-0.3207

0.023

0.7164

0.001

ESR

-0.4283

0.001

-0.3981

0.001

0.5467

0.001

Anti-U1RNP (U/ml)

-0.0486

0.7371

-0.0694

0.6316

0.4182

0.0025

Anti-CL IgG (U/ml)

-0.0717

0.6206

-0.0411

0.776

0.2236

0.1184

AECA (IU/ml)

-0.3075

0.029

-0.2686

0.0592

0.2890

0.0417

Thrombomodulin (ng/ml)

-0.0642

0.6577

-0.0165

0.9089

0.4823

0.00038

vWFAg (%)

-0.0122

0.9329

-0.2692

0.058

0.5443

0.001


AECA, anti-endothelial cell antibody; anti-CL, anti-cardiolipin; anti-U1RNP, anti-U1 ribonucleoprotein; ESR, erythrocyte sedimentation rate; FMD, flow-mediated dilation; hs-CRP, high-sensitivity C-reactive protein; IMT, intima-media thickness; MCTD, mixed connective tissue disease; NMD, nitrate-mediated dilation; vWFAg, von Willebrand factor antigen. aSpearman rank correlation.

Soltesz et al. Arthritis Research & Therapy 2010 12:R78   doi:10.1186/ar2999

Open Data