Table 5

Independent correlates of total cholesterol determined by using multivariate linear regression (GEE)

Variablea

Parameter estimate

95% CI

P value


Age (years)

0.009

0.004, 0.014

0.0005

SLEDAI-2K scoreb

0.04

0.03, 0.05

< 0.0001

Corticosteroids

0.32

0.22, 0.42

< 0.0001

Antimalarialsc

-0.42

-0.53, -0.32

< 0.0001

Immunosuppressivesd

0.17

0.06, 0.27

0.0017

Antihypertensivese

0.19

0.08, 0.30

0.0009

Hypertensionf

0.34

0.22, 0.46

< 0.0001


GEE, generalized estimating equation; CI, confidence interval.

aAll variables measured coincident with measurement of total cholesterol.

bSLE Disease Activity Index 2000; scores range from 0 to 105, with higher scores indicating more-active disease.

cAntimalarials include chloroquine and hydroxychloroquine.

d Immunosuppressives include methotrexate, azathioprine, mycophenolate mofetil,

cyclosporine, and cyclophosphamide.

eAntihypertensives include all classes of drugs used to lower blood pressure.

fHypertension is defined as systolic BP ≥ 140 mm Hg or diastolic BP ≥ 90 mm Hg.

Nikpour et al. Arthritis Research & Therapy 2010 12:R125   doi:10.1186/ar3063

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