Gene expression in skin (A) or lung samples (B) with different treatments. Four mice were used for each treatment. The relative transcript levels of Col1a2, Col3a1, Ctgf, SPARC and Ccl2 in siRNA-treated or untreated bleomycin-induced skins or lungs, respectively. The expression level of each gene in the skin or lung sample from saline treated mice was normalized to 1. Treatments: Saline; BLM (bleomycin); BLM + Ctgf siRNA and BLM + SPARC siRNA. *, P < 0.05.
Wang et al. Arthritis Research & Therapy 2010 12:R60 doi:10.1186/ar2973