Correlation of Th17 and Th1 response is dysregulated in patients with SLE. (a) The frequency (% of CD4+IL-17+ T cells correlates with the frequency of CD4+IFN-γ+ T cells in healthy control subjects (HC, n = 26) but not in patients with SLE (n = 25). (b) Patients with SLE have a higher Th17/Th1 ratio (frequency of CD4+IL-17+ T cells/frequency of CD4+IL-IFN-γ+ T cells) compared with healthy control subjects. Bars and numbers in (b) indicate the means.
Shah et al. Arthritis Research & Therapy 2010 12:R53 doi:10.1186/ar2964