Table 1

Results from WTCCC RA GWAS in ROBO3 gene region

SNP

Position ^a

P value ^b

Function

rs653403

124,201,501

0.329954

5' intergenic ROBO3

rs610104

124,213,908

0.217045

5' intergenic ROBO3

rs10790711

124,219,899

0.0341778

5' intergenic ROBO3

rs733601

124,220,090

0.762976

5' intergenic ROBO3

rs1940177

124,223,175

0.859324

5' intergenic ROBO3

rs11604758

124,226,213

0.00078241

5' intergenic ROBO3

rs11219814

124,233,333

0.184905

5' intergenic ROBO3

rs4936957

124,245,198

0.0184723

Intron 4ROBO3

rs3923890

124,245,620

0.00875808

Intron 5ROBO3

rs10790714

124,255,238

0.0629092

Intron 26 ROBO3

rs4326810

124,255,347

0.163546

Intron 26 ROBO3

rs12823

124,259,821

0.0722958

3' UTR ROBO4

rs11219831

124,267,979

0.421456

Intron 10 ROBO4

rs11219832

124,272,500

0.703442

Intron 1 ROBO4

rs4077566

124,276,481

0.0658315

5' intergenic ROBO4

^a on chromosome 11 (hg18).

^b additive model.

Nominal significant results are displayed in bold.

GWAS, genome-wide association study; RA, rheumatoid arthritis; SNP, single nucleotide protocol; WTCCC, Wellcome Trust Case Control Consortium.

Denk et al. Arthritis Research & Therapy 2010 12:R45   doi:10.1186/ar2955