Table 2

Annualized observed rates of progression of disability and loss of health status in rheumatoid arthritis

Variable

All patients

(N = 18,485)

Rate (95% CI)

Biologics never used

(N = 10,265)

Rate (95% CI)

Biologics ever used

(N = 8,220)

Rate (95% CI)


HAQ

0.013 (0.010, 0.015)

0.016 (0.013, 0.019)

0.010 (0.007, 0.013)

PCS

0.035 (0.001, 0.069)

-0.003 (-0.048, 0.041)

0.068 (0.022, 0.114)

MCS

0.039 (0.008, 0.069)

0.001 (-0.041, 0.063)

0.044 (-0.003, 0.090)

EQ-5D

0.001 (0.001, 0.002)

-0.000 (-0.001, 0.001)

0.002 (0.012, 0.003)


Annualized observed rates of progression of disability and loss of health status in 18,485 RA patients during up to 10 years of observation.

Positive rates indicate worsening HAQ disability. Negative rates indicate worsening health status for MCS, PCS, and EQ-5D.

HAQ, Health Assessment Questionnaire; PCS, SF-36 Physical Component Summary; MCS, SF-36 Mental Component Summary.

Wolfe and Michaud Arthritis Research & Therapy 2010 12:R35   doi:10.1186/ar2944

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