Table 1 |
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|
Candidate genes identified from rheumatoid arthritis genome-wide association studies |
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| Gene |
GeneID |
PMID |
Gene expression (up or down) |
Microarray P valuesa |
|
|
||||
| CD244 |
605554 |
18794858 |
Up |
1.0 × 10-16 |
| PADI4 |
605347 |
12833157 |
Up |
2.32 × 10-5 |
| SLC22A2 |
602608 |
14608356 |
Up |
1.94 × 10-6 |
| PTPN22 |
600716 |
15208781 |
Up |
9.66 × 10-8 |
| CTLA4 |
123890 |
16380915 |
No change |
0.767 |
| STAT4 |
600558 |
17804842 |
Up |
1.38 × 10-8 |
|
|
||||
|
aP values determined by comparison between 112 rheumatoid arthritis patients and 45 healthy individuals. |
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|
Sugino et al. Arthritis Research & Therapy 2010 12:401 doi:10.1186/ar2937 |
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