Table 4

Previously identified marker

Gene description

Gene symbol

AC mean

AF mean

NP mean

Fold change (NP/AC)

Fold change (NP/AF)

Fold change (NP/AC&AF)


matrix metallopeptidase 2

MMP2

200.20

155.41

121.53

-1.65

-1.28

-1.56

solute carrier family 2, member 1

SLC2A1

1200.57

1211.32

1281.16

1.07

1.06

1.04

hypoxia-inducible factor 1, alpha

HIF1A

3985.62

7783.65

2552.07

-1.56

-3.05

-2.50

vascular endothelial growth factor

VEGF

1874.33

5661.88

2233.09

1.19

-2.54

-1.86

CD24 molecule

CD24

521.84

44.59

86.75

-6.02

1.95

-3.42


keratin 19

KRT19

0.91

0.65

32.59

35.81

50.47

19.88

glypican 3

GPC3

4.24

37.63

13.28

3.13

-2.83

-1.78

annexin A3

ANXA3

7.64

63.66

8.26

1.08

-7.71

-7.44

pleiotrophin

PTN

208.08

54.11

1.10

-189.18

-49.19

-152.58

vimentin

VIM

4625.18

4749.33

3508.86

-1.32

-1.35

-1.35

cartilage oligomeric matrix protein

COMP

6053.50

2986.89

2786.96

-2.17

-1.07

-1.78

matrix Gla protein

MGP

8480.52

7742.10

2865.30

-2.96

-2.70

-3.21


alpha-2-macroglobulin

A2M

9.49

26.62

11.37

1.20

-2.34

-1.77

annexin A4

ANXA4

1223.21

2318.40

1273.29

1.04

-1.82

-1.55

desmocollin 2

DSC2

1.88

140.72

68.18

36.30

-2.06

-1.22

keratin 18

KRT18

0.01

0.04

94.10

15990.45

2647.60

1860.77

neural cell adhesion molecule 1

NCAM1

0.76

0.94

12.64

16.55

13.43

10.06


Bovine microarray data for previously identified markers. Mean fluorescence intensity expression is shown for each cell type (AC, AF and NP) along with the calculated fold change values. AC, articular cartilage; AF, annulus fibrosus; NP, nucleus pulposus.

Minogue et al. Arthritis Research & Therapy 2010 12:R22   doi:10.1186/ar2929

Open Data