Arthritis Research & Therapy

official impact factor 4.36

Open Access Research article

Autophagy induction and CHOP under-expression promotes survival of fibroblasts from rheumatoid arthritis patients under endoplasmic reticulum stress

Yong-Joo Shin1, Song-Hee Han2, Do-Sung Kim2, Geum-Hwa Lee2, Wan-Hee Yoo3, Yong-Mo Kang4, Je-Yong Choi5, Yong C Lee6,7, Seoung J Park6,7, Seul-Ki Jeong8, Hyung-Tae Kim9, Soo-Wan Chae2, Hyun-Ja Jeong10, Hyung-Ryong Kim11 and Han-Jung Chae2,7*

Author Affiliations

1 Department of Rheumatology, Medical School, the Catholic University of Korea, Seoul, Republic of Korea, 150-713

2 Department of Pharmacology and Cardiovascular Research Institute, Medical School, Chonbuk University, Jeonju, Chonbuk, Republic of Korea, 561-181

3 Division of Rheumatology, Department of Internal Medicine, Medical School, Chonbuk University, Jeonju, Chonbuk, Republic of Korea, 561-181

4 Division of Rheumatology, Department of Internal Medicine, Kyungpook University Hospital, Daegu, Republic of Korea, 561-181

5 Department of Biochemistry and Cell Biology, School of Medicine, Kyungpook University, Daegu, Republic of Korea, 110-749

6 Department of Internal Medicine, Medical School, Chonbuk Univ, Jeonju, Republic of Korea, 561-181

7 Research Center for Pulmonary Disorders, Chonbuk Hospital, Jeonju, Republic of Korea, 561-181

8 Department of Neurology, Medical School, Chonbuk University, Jeonju, Chonbuk, Republic of Korea, 561-181

9 Department of Anatomy, Medical School, Chonbuk University, Jeonju, Chonbuk, Republic of Korea, 561-181

10 Biochip Research Center, Hoseo University, Chungnam, Republic of Korea, 336-795

11 Department of Dental Pharmacology, Dental School, Wonkwang University, Iksan, Chonbuk, Republic of Korea, 570-749

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Arthritis Research & Therapy 2010, 12:R19 doi:10.1186/ar2921

Published: 1 February 2010

Additional files

Additional file 1:

Electron microscopy data. Electron microscopy data from thapsigargin (1 μM)-treated OASF and RASF.

Format: JPEG Size: 52KB Download file

Open Data