Table 4

Association between lipids and annual change in total tibial cartilage volume

Univariate analysis, regression coefficient

(95% CI)

P value

Multivariate analysis, regression coefficient

(95% CI)^a

P value

Total cholesterol

-0.24 (-12.77, 12.28)

0.97

-1.77 (-11.35, 14.88)

0.79

Ln triglycerides

0.70 (-32.48, 33.88)

0.97

12.6 (-24.12, 49.32)

0.49

Ln HDL

-4.78 (-56.43, 46.88)

0.85

-15.96 (-72.28, 40.37)

0.58

Ln LDL

3.16 (-48.06, 54.39)

0.90

13.12 (-41.2, 67.45)

0.63

Total/HDL ratio

-0.67 (-11.57, 10.24)

0.90

2.58 (-9.5, 14.68)

0.67

^aAnnual change in total tibial cartilage volume (in microlitres) for each unit increase in total cholesterol, natural logarithm (Ln) of triglycerides, natural logarithm of high-density lipoprotein (HDL) or low-density lipoprotein (LDL) or for the total/HDL ratio after adjusting for age and body mass index. CI, confidence interval.

Davies-Tuck et al. Arthritis Research & Therapy 2009 11:R181   doi:10.1186/ar2873