Table 3

Association between incident bone marrow lesions and lipids

Univariate analysis, odds ratio

(95% CI)

P value

Multivariate analysis, odds ratio

(95% CI)^a

P value

Total cholesterol

1.82 (1.04, 3.2)

0.037

1.84 (1.01, 3.36)

0.048

Ln triglycerides

9.23 (2.06, 41.46)

0.004

8.4 (1.63, 43.43)

0.01

Ln HDL

0.60 (0.06, 5.99)

0.67

1.12 (0.008, 14.79)

0.93

Ln LDL

7.10 (0.56, 89.39)

0.13

5.79 (0.39,86.46)

0.20

Total/HDL ratio

1.53 (0.98, 2.38)

0.06

1.41 (0.86, 2.32)

0.17

^aOdds ratio of having an incident bone marrow lesion for each unit increase in total cholesterol, natural logarithm (Ln) of triglycerides, natural logarithm of high-density lipoprotein (HDL) or low-density lipoprotein (LDL) or for the total/HDL ration after adjusting for age and body mass index. CI, confidence interval.

Davies-Tuck et al. Arthritis Research & Therapy 2009 11:R181   doi:10.1186/ar2873