Table 5 |
||
|
Incidence of adverse events |
||
|
Adverse events |
CCII (n = 326) |
MTX (n = 177) |
|
|
||
|
Nausea, vomiting |
6 |
13 |
|
Abdominal pain, epigastric discomfort |
17 |
11 |
|
Diarrhea |
0 |
2 |
|
Liver dysfunction |
6 |
10 |
|
Headache, dizziness |
3 |
5 |
|
Itching, rash |
5 |
1 |
|
Blood in urine |
2 |
3 |
|
Constipation |
1 |
0 |
|
Edema |
2 |
1 |
|
Alopecia |
0 |
1 |
|
Decrease in white blood cell count |
1 |
5 |
|
Decrease in platelet count |
0 |
1 |
|
Sum of events |
43 |
53 |
|
|
||
|
CCII, chicken type II collagen; MTX, methotrexate. |
||
|
Wei et al. Arthritis Research & Therapy 2009 11:R180 doi:10.1186/ar2870 |
||
