Table 1

Patient profile with active/inactive rheumatoid arthritis

Active RA

(n = 20)

Inactive RA

(n = 19)

P value


CRP (mg/ml)

3.38 ± 2.83

< 0.3

P < 0.01

ESR (mm/h)

69.9 ± 29.7

19.5 ± 13.2

P < 0.05

WBC (cells/ml3)

8235 ± 3200

5470 ± 552

P < 0.05

MMP-3 (ng/ml)

402.0 ± 307.9

103.1 ± 73.3

P < 0.05

Frequency of CTGF elevated sera

35.0% (7/20)

5.3% (1/19)

P < 0.05


CTGF = connective tissue growth factor; RA = rheumatoid arthritis; CRP = C reactive protein; ESR = erythrocyte sedimentation rate; WBC = white blood cell; MMP = matrix metalloproteinase.

Nozawa et al. Arthritis Research & Therapy 2009 11:R174   doi:10.1186/ar2863

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