Arthritis Research & Therapy

official impact factor 4.36

Open Access Research article

Insights in to the pathogenesis of axial spondyloarthropathy based on gene expression profiles

Srilakshmi M Sharma1, Dongseok Choi2, Stephen R Planck3,4,1, Christina A Harrington5, Carrie R Austin1, Jinnell A Lewis1, Tessa N Diebel1, Tammy M Martin1,6, Justine R Smith3,1 and James T Rosenbaum3,4,1*

Author Affiliations

1 Casey Eye Institute, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, Portland, Oregon, 97239, USA

2 Department of Public Health & Preventive Medicine, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, Portland, Oregon, 97239, USA

3 Department of Cell & Developmental Biology, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, Portland, Oregon, 97239, USA

4 Department of Medicine, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, Portland, Oregon, 97239, USA

5 Gene Microarray Shared Resource, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, Portland, Oregon, 97239, USA

6 Department of Molecular Microbiology & Immunology, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, Portland, Oregon, 97239, USA

For all author emails, please log on.

Arthritis Research & Therapy 2009, 11:R168 doi:10.1186/ar2855

Published: 9 November 2009

Additional files

Additional file 1:

PDF file containing heatmaps illustrating expression of genes distinguishing control and axial spondyloarthropathy (SpA) peripheral blood in Set 1 and Set 2.

Format: PDF Size: 1.4MB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data

Additional file 2:

PDF file containing a table that lists probe sets indicating genes with significantly (q < 5%) higher or lower expression in patients with axial spondyloarthropathy compared with control subjects in Set 1 and Set 2.

Format: PDF Size: 106KB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data