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Synergistic chondroprotective effects of curcumin and resveratrol in human articular chondrocytes: inhibition of IL-1β-induced NF-κB-mediated inflammation and apoptosis

Constanze Csaki, Ali Mobasheri and Mehdi Shakibaei*

Arthritis Research & Therapy 2009, 11:R165 doi:10.1186/ar2850

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Curcumin mediated suppression of nuclear factor-κB promotes chondrogenic differentiation of mesenchymal stem cells in a high-density co-culture microenvironment

Constanze Buhrmann, Ali Mobasheri, Ulrike Matis, Mehdi Shakibaei Arthritis Research & Therapy 2010, 12:R127 (1 July 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Curcumin, a naturally-occurring nuclear factor-KB inhibitor, protects mesenchymal stem cells (MSCs) from the harmful effects of pro-inflammatory cytokines, thereby establishing a suitable microenvironment for MSCs to undergo chondrogenesis.

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