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Volume 11 Issue 6

Comment

Editorial   Free

SAPHO syndrome: Is a range of pathogen-associated rheumatic diseases extended?

Alexander P Rozin Arthritis Research & Therapy 2009, 11:131 (5 November 2009)

Abstract | Full text | PDF | PubMed

Editorial   Free Highly Accessed

Immunocytokines: the long awaited therapeutic magic bullet in rheumatoid arthritis?

Fons van de Loo, Wim van den Berg Arthritis Research & Therapy 2009, 11:132 (6 November 2009)

Abstract | Full text | PDF | PubMed

Editorial   Free

TWEAK: a novel biomarker for lupus nephritis?

Neeraj Dhaun, David C Kluth Arthritis Research & Therapy 2009, 11:133 (17 November 2009)

Abstract | Full text | PDF | PubMed

Editorial   Free Highly Accessed

Rituximab treatment in rheumatoid arthritis: how does it work?

Maria JH Boumans, Paul P Tak Arthritis Research & Therapy 2009, 11:134 (24 November 2009)

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Editorial   Free

Microparticles as biomarkers in autoimmunity: from dust bin to center stage

David S Pisetsky Arthritis Research & Therapy 2009, 11:135 (30 November 2009)

Abstract | Full text | PDF | PubMed

Editorial   Free

The role of anti-α-actinin antibodies in the pathogenesis and monitoring of lupus nephritis

Pierre Youinou, Chaim Putterman Arthritis Research & Therapy 2009, 11:137 (11 December 2009)

Abstract | Full text | PDF | PubMed

Editorial   Free

The 'RASor's' edge: Ras proteins and matrix destruction in arthritis

Adam C Schmucker, Constance E Brinckerhoff Arthritis Research & Therapy 2009, 11:136 (11 December 2009)

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Editorial   Free Highly Accessed

Effective rheumatoid arthritis treatment requires comprehensive management strategies

Chad S Boomershine Arthritis Research & Therapy 2009, 11:138 (21 December 2009)

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Review

Review   Free

Biomarkers as tools for improved diagnostic and therapeutic monitoring in systemic lupus erythematosis

Michael F Smith, Falk Hiepe, Thomas Dörner, Gerd Burmester Arthritis Research & Therapy 2009, 11:255 (19 November 2009)

Abstract | Full text | PDF | PubMed

Review   Free

Utility of synovial biopsy

Stefan Vordenbäumen, Leo AB Joosten, Johannes Friemann, Matthias Schneider, Benedikt Ostendorf Arthritis Research & Therapy 2009, 11:256 (23 November 2009)

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Review   Free Highly Accessed

Heterogeneity of human effector CD4+ T cells

Francesco Annunziato, Sergio Romagnani Arthritis Research & Therapy 2009, 11:257 (9 December 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Review   Free

Treatment of Lyme borreliosis

Hermann J Girschick, Henner Morbach, Dennis Tappe Arthritis Research & Therapy 2009, 11:258 (17 December 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Report

Meeting report   Free

Kitasato Symposium 2009: New Prospects for Cytokine Inhibition

Gerd R Burmester, Peter E Lipsky, Thomas Dörner, the Kitasato Meeting Faculty* Arthritis Research & Therapy 2009, 11:301 (23 December 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research

Research article   Open Access

Adiponectin may contribute to synovitis and joint destruction in rheumatoid arthritis by stimulating vascular endothelial growth factor, matrix metalloproteinase-1, and matrix metalloproteinase-13 expression in fibroblast-like synoviocytes more than proinflammatory mediators

Hyun-Mi Choi, Yeon-Ah Lee, Sang-Hoon Lee, Seung-Jae Hong, Dae-Hyun Hahm, Sang-Yun Choi, Hyung-In Yang, Myung Chul Yoo, Kyoung Soo Kim Arthritis Research & Therapy 2009, 11:R161 (2 November 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access

Dual energy x-ray absorptiometry analysis contributes to the prediction of hip osteoarthritis progression

Martha C Castaño Betancourt, Jacqueline C Van der Linden, Fernando Rivadeneira, Rianne M Rozendaal, Sita M Bierma Zeinstra, Harrie Weinans, Jan H Waarsing Arthritis Research & Therapy 2009, 11:R162 (2 November 2009)

Abstract | Full text | PDF | PubMed | F1000

Research article   Open Access Highly Accessed

ACR70-disease activity score remission achievement from switches between all the available biological agents in rheumatoid arthritis: a systematic review of the literature

Stefano Alivernini, Antonella Laria, Elisa Gremese, Angelo Zoli, Gianfranco Ferraccioli Arthritis Research & Therapy 2009, 11:R163 (3 November 2009)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Sinus aspergilloma in rheumatoid arthritis before or during tumor necrosis factor-alpha antagonist therapy

Ariane Leboime, Jean-Marie Berthelot, Yannick Allanore, Lama Khalil-Kallouche, Philippe Herman, Philippe Orcel, Frédéric Lioté Arthritis Research & Therapy 2009, 11:R164 (3 November 2009)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Synergistic chondroprotective effects of curcumin and resveratrol in human articular chondrocytes: inhibition of IL-1β-induced NF-κB-mediated inflammation and apoptosis

Constanze Csaki, Ali Mobasheri, Mehdi Shakibaei Arthritis Research & Therapy 2009, 11:R165 (4 November 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | F1000

Research article   Open Access

Effect of small interference RNA (siRNA) for ADAMTS5 on intervertebral disc degeneration in the rabbit anular needle-puncture model

Shoji Seki, Yumiko Asanuma-Abe, Koichi Masuda, Yoshiharu Kawaguchi, Kunihiro Asanuma, Carol Muehleman, Akiko Iwai, Tomoatsu Kimura Arthritis Research & Therapy 2009, 11:R166 (4 November 2009)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Altered peptide ligands inhibit arthritis induced by glucose-6-phosphate isomerase peptide

Keiichi Iwanami, Isao Matsumoto, Yohei Yoshiga, Asuka Inoue, Yuya Kondo, Kayo Yamamoto, Yoko Tanaka, Reiko Minami, Taichi Hayashi, Daisuke Goto, Satoshi Ito, Yasuharu Nishimura, Takayuki Sumida Arthritis Research & Therapy 2009, 11:R167 (9 November 2009)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Insights in to the pathogenesis of axial spondyloarthropathy based on gene expression profiles

Srilakshmi M Sharma, Dongseok Choi, Stephen R Planck, Christina A Harrington, Carrie R Austin, Jinnell A Lewis, Tessa N Diebel, Tammy M Martin, Justine R Smith, James T Rosenbaum Arthritis Research & Therapy 2009, 11:R168 (9 November 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access

Influence of cytokine inhibitors on concentration and activity of MMP-1 and MMP-3 in disc herniation

Stéphane Genevay, Axel Finckh, Françoise Mezin, Enrico Tessitore, Pierre-André Guerne Arthritis Research & Therapy 2009, 11:R169 (11 November 2009)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Rapid and sustained improvements in health-related quality of life, fatigue, and other patient-reported outcomes in rheumatoid arthritis patients treated with certolizumab pegol plus methotrexate over 1 year: results from the RAPID 1 randomized controlled trial

Vibeke Strand, Philip Mease, Gerd R Burmester, Enkeleida Nikaï, Geoffroy Coteur, Ronald van Vollenhoven, Bernard Combe, Edward C Keystone, Arthur Kavanaugh Arthritis Research & Therapy 2009, 11:R170 (12 November 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access

HLA-E gene polymorphism associates with ankylosing spondylitis in Sardinia

Fabiana Paladini, Francesca Belfiore, Elisa Cocco, Carlo Carcassi, Alberto Cauli, Alessandra Vacca, Maria Fiorillo, Alessandro Mathieu, Isabella Cascino, Rosa Sorrentino Arthritis Research & Therapy 2009, 11:R171 (13 November 2009)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Intradiscal injection of simvastatin retards progression of intervertebral disc degeneration induced by stab injury

Huina Zhang, Lin Wang, Jun Beom Park, Paul Park, Victor C Yang, Scott J Hollister, Frank La Marca, Chia-Ying Lin Arthritis Research & Therapy 2009, 11:R172 (13 November 2009)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Aggrecanolysis and in vitro matrix degradation in the immature bovine meniscus: mechanisms and functional implications

Christopher G Wilson, Eric J Vanderploeg, Fengrong Zuo, John D Sandy, Marc E Levenston Arthritis Research & Therapy 2009, 11:R173 (17 November 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access

Connective tissue growth factor promotes articular damage by increased osteoclastogenesis in patients with rheumatoid arthritis

Kazuhisa Nozawa, Maki Fujishiro, Mikiko Kawasaki, Hiroshi Kaneko, Kazuhisa Iwabuchi, Mitsuaki Yanagida, Fujihiko Suzuki, Keiji Miyazawa, Yoshinari Takasaki, Hideoki Ogawa, Kenji Takamori, Iwao Sekigawa Arthritis Research & Therapy 2009, 11:R174 (18 November 2009)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Detection of Chlamydia trachomatis-DNA in synovial fluid: evaluation of the sensitivity of different DNA extraction methods and amplification systems

Julia Freise, Iris Bernau, Sabine Meier, Henning Zeidler, Jens G Kuipers Arthritis Research & Therapy 2009, 11:R175 (21 November 2009)

Abstract | Full text | PDF | PubMed

Research article   Open Access

CTLA4-Ig interacts with cultured synovial macrophages from rheumatoid arthritis patients and downregulates cytokine production

Maurizio Cutolo, Stefano Soldano, Paola Montagna, Alberto Sulli, Bruno Seriolo, Barbara Villaggio, Pierfranco Triolo, Paolo Clerico, Lamberto Felli, Renata Brizzolara Arthritis Research & Therapy 2009, 11:R176 (23 November 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access Highly Accessed

Inflammatory bowel disease serologies in ankylosing spondylitis patients: a pilot study

Matthew L Mundwiler, Ling Mei, Carol J Landers, John D Reveille, Stephan Targan, Michael H Weisman Arthritis Research & Therapy 2009, 11:R177 (23 November 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access Highly Accessed

Infliximab concentration monitoring improves the control of disease activity in rheumatoid arthritis

Denis Mulleman, Jean-Camille Méric, Gilles Paintaud, Emilie Ducourau, Charlotte Magdelaine-Beuzelin, Jean-Pierre Valat, Philippe Goupille, the Centre National de la Recherche Scientifique UMR 6239 GICC Arthritis Research & Therapy 2009, 11:R178 (25 November 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access Highly Accessed

Safety of TNF-blocking agents in rheumatic patients with serology suggesting past hepatitis B state: results from a cohort of 21 patients

Caroline Charpin, Sandrine Guis, Philippe Colson, Patrick Borentain, Jean-Pierre Mattéi, Patrice Alcaraz, Nathalie Balandraud, Benoit Thomachot, Jean Roudier, René Gérolami Arthritis Research & Therapy 2009, 11:R179 (26 November 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access Highly Accessed

A multicenter, double-blind, randomized, controlled phase III clinical trial of chicken type II collagen in rheumatoid arthritis

Wei Wei, Ling-Ling Zhang, Jian-Hua Xu, Feng Xiao, Chun-De Bao, Li-Qing Ni, Xing-Fu Li, Yu-Qing Wu, Ling-Yun Sun, Rong-Hua Zhang, Bao-Liang Sun, Sheng-Qian Xu, Shang Liu, Wei Zhang, Jie Shen, Hua-Xiang Liu, Ren-Cheng Wang Arthritis Research & Therapy 2009, 11:R180 (1 December 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

A randomised controlled trial has shown that chicken type II collagen is a safe and effective treatment for rheumatoid arthritis, and may be a potential alternative therapy to methotrexate.

Research article   Open Access

Total cholesterol and triglycerides are associated with the development of new bone marrow lesions in asymptomatic middle-aged women - a prospective cohort study

Miranda L Davies-Tuck, Fahad Hanna, Susan R Davis, Robin J Bell, Sonia L Davison, Anita E Wluka, Jenny Adams, Flavia M Cicuttini Arthritis Research & Therapy 2009, 11:R181 (4 December 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access

Psychological correlates of self-reported functional limitation in patients with ankylosing spondylitis

Tamar F Brionez, Shervin Assassi, John D Reveille, Thomas J Learch, Laura Diekman, Michael M Ward, John C Davis, Michael H Weisman, Perry Nicassio Arthritis Research & Therapy 2009, 11:R182 (7 December 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | F1000

Research article   Open Access

Comparative, double-blind, controlled study of intra-articular hyaluronic acid (Hyalubrix®) injections versus local anesthetic in osteoarthritis of the hip

Alberto Migliore, Umberto Massafra, Emanuele Bizzi, Francesca Vacca, Severino Martin-Martin, Mauro Granata, Andrea Alimonti, Sandro Tormenta Arthritis Research & Therapy 2009, 11:R183 (9 December 2009)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Matrix metalloproteinase 28, a novel matrix metalloproteinase, is constitutively expressed in human intervertebral disc tissue and is present in matrix of more degenerated discs

Helen E Gruber, Jane A Ingram, Gretchen L Hoelscher, Natalia Zinchenko, H James Norton, Edward N Hanley Arthritis Research & Therapy 2009, 11:R184 (9 December 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access Highly Accessed

A combination of methotrexate and zoledronic acid prevents bone erosions and systemic bone mass loss in collagen induced arthritis

Benoit Le Goff, Elise Soltner, Céline Charrier, Yves Maugars, Françoise Rédini, Dominique Heymann, Jean-Marie Berthelot Arthritis Research & Therapy 2009, 11:R185 (10 December 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access

Predictors of the first cardiovascular event in patients with systemic lupus erythematosus - a prospective cohort study

Johanna Gustafsson, Iva Gunnarsson, Ola Börjesson, Susanne Pettersson, Sonia Möller, Guo-Zhong Fei, Kerstin Elvin, Julia F Simard, Lars-Olof Hansson, Ingrid E Lundberg, Anders Larsson, Elisabet Svenungsson Arthritis Research & Therapy 2009, 11:R186 (10 December 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access

RANKL inhibition by osteoprotegerin prevents bone loss without affecting local or systemic inflammation parameters in two rat arthritis models: comparison with anti-TNFα or anti-IL-1 therapies

Marina Stolina, Georg Schett, Denise Dwyer, Steven Vonderfecht, Scot Middleton, Diane Duryea, Efrain Pacheco, Gwyneth Van, Brad Bolon, Ulrich Feige, Debra Zack, Paul Kostenuik Arthritis Research & Therapy 2009, 11:R187 (11 December 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access Highly Accessed

Serum levels of autoantibodies against C-reactive protein correlate with renal disease activity and response to therapy in lupus nephritis

Christopher Sjöwall, Agneta Zickert, Thomas Skogh, Jonas Wetterö, Iva Gunnarsson Arthritis Research & Therapy 2009, 11:R188 (11 December 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access

Local expression of tumor necrosis factor-receptor 1:immunoglobulin G can induce salivary gland dysfunction in a murine model of Sjögren's syndrome

Jelle L Vosters, Hongen Yin, Nienke Roescher, Marc R Kok, Paul P Tak, John A Chiorini Arthritis Research & Therapy 2009, 11:R189 (14 December 2009)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Separating therapeutic efficacy from glucocorticoid side-effects in rodent arthritis using novel, liposomal delivery of dexamethasone phosphate: long-term suppression of arthritis facilitates interval treatment

Una Rauchhaus, Franz Schwaiger, Steffen Panzner Arthritis Research & Therapy 2009, 11:R190 (15 December 2009)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Better assessment of physical function: item improvement is neglected but essential

Bonnie Bruce, James F Fries, Debbie Ambrosini, Bharathi Lingala, Barbara Gandek, Matthias Rose, John E Ware Arthritis Research & Therapy 2009, 11:R191 (16 December 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access Highly Accessed

Phytalgic®, a food supplement, vs placebo in patients with osteoarthritis of the knee or hip: a randomised double-blind placebo-controlled clinical trial

Alain Jacquet, Pierre-Olivier Girodet, Antoine Pariente, Karelle Forest, Laurent Mallet, Nicholas Moore Arthritis Research & Therapy 2009, 11:R192 (16 December 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | F1000 |  Editor’s summary

A food supplement containing fish oils, Urtica dioica (the common nettle), zinc and vitamin E decreases the need for painkillers and reduces symptoms of osteoarthritis, a randomised trial has found.

Research article   Open Access

Immunoglobulin G galactosylation and sialylation are associated with pregnancy-induced improvement of rheumatoid arthritis and the postpartum flare: results from a large prospective cohort study

Fleur E van de Geijn, Manfred Wuhrer, Maurice HJ Selman, Sten P Willemsen, Yaël A de Man, André M Deelder, Johanna MW Hazes, Radboud JEM Dolhain Arthritis Research & Therapy 2009, 11:R193 (16 December 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access

Interleukin-23 is critical for full-blown expression of a non-autoimmune destructive arthritis and regulates interleukin-17A and RORγt in γδ T cells

Ferry Cornelissen, Adriana MC Mus, Patrick S Asmawidjaja, Jan van Hamburg, Joel Tocker, Erik Lubberts Arthritis Research & Therapy 2009, 11:R194 (17 December 2009)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Active immunization to tumor necrosis factor-α is effective in treating chronic established inflammatory disease: a long-term study in a transgenic model of arthritis

Laure Delavallée, Luca Semerano, Eric Assier, Géraldine Vogel, Grégoire Vuagniaux, Marion Laborie, Daniel Zagury, Natacha Bessis, Marie-Christophe Boissier Arthritis Research & Therapy 2009, 11:R195 (23 December 2009)

Abstract | Full text | PDF | PubMed | F1000


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