Table 3 |
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|
Chemokine-receptor expression in SF and PB CD27- switch memory B cells |
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|
Chemokine receptors |
Synovial fluida(n = 13) |
Peripheral blooda(n = 13) |
P valueb |
|
|
|||
|
CCR1 |
5.4 (2.0-30) |
5.1 (4.7-5.9) |
ns |
|
CCR2 |
5.7 (1.0-34) |
5.2 (3.4-6.6) |
Ns |
|
CCR3 |
7.1 (4.0-28.1) |
6.5 (5.7-7.0) |
ns |
|
CCR4 |
6.0 (2.3-19.7) |
5.1 (3.9-5.9) |
ns |
|
CCR5 |
16.1 (3.4-31.9) |
2.1 (1.6-4.4) |
0.0001 |
|
CCR6 |
6.3 (2.0-20) |
36.8 (27.8-69.7) |
0.0003 |
|
CCR7 |
21.3 (5.0-68) |
65.1 (40.2-72.7) |
0.0034 |
|
CCR8 |
11.5 (4.3-38) |
4.9 (3.0-7.0) |
0.025 |
|
CCR9 |
12.7 (6.1-35) |
5.5 (4.9-9.3) |
0.0041 |
|
CXCR1 |
4.2 (0.2-9.1) |
1.5 (1-3.5) |
ns |
|
CXCR2 |
18.2 (15.8-22.5) |
4.7 (3.8-6.1) |
0.0011 |
|
CXCR3 |
49.5 (41.8-78) |
6.5 (4-12.3) |
0.0011 |
|
CXCR4 |
43.1 (30.5-54.8) |
67.5 (33.5-90.8) |
ns |
|
CXCR5 |
31.6 (20-57.1) |
78.4 (63.4-91) |
0.0006 |
|
|
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|
aResults represent median percentage of positive cells as assessed with flow cytometry. Values in parentheses are minimum and maximum values. bP values were calculated by comparing the results of JIA SF and PB cell staining. ns = not significant. |
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|
Corcione et al. Arthritis Research & Therapy 2009 11:R150 doi:10.1186/ar2824 |
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