Suppressive effect of secretory phospholipase A2 inhibitory peptide on interleukin-1β-induced matrix metalloproteinase production in rheumatoid synovial fibroblasts, and its antiarthritic activity in hTNFtg mice

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Suppressive effect of secretory phospholipase A₂inhibitory peptide on interleukin-1β-induced matrix metalloproteinase production in rheumatoid synovial fibroblasts, and its antiarthritic activity in hTNFtg mice

Maung-Maung Thwin, Eleni Douni, Pachiappan Arjunan, George Kollias, Prem V Kumar and Ponnampalam Gopalakrishnakone^*

Arthritis Research & Therapy 2009, 11:R138 doi:10.1186/ar2810