Major differences of peripheral B-cell compartments between systemic lupus erythematosus (SLE) patients and normal controls as shown in a representative dot plot. Please note the increased frequency of Ig-class-switched CD27+ memory B cells and CD27-/IgD- B cells. ND, normal donors.
Dörner et al. Arthritis Research & Therapy 2009 11:247 doi:10.1186/ar2780