Table 4

Drugs approved by the Food and Drugs Administration for treatment of fibromyalgia

Drug

Class

Mechanism


Duloxetine

Antidepressant

Balanced norepinephrine and serotonin reuptake inhibition

Milnacipran

Antidepressant

Balanced norepinephrine and serotonin reuptake inhibition

Pregabalin

Anticonvulsant

α2δ ligand; affects calcium influx and release of excitatory amino acids and neuropeptides


Buskila Arthritis Research & Therapy 2009 11:242   doi:10.1186/ar2720