Predicting joint damage in rheumatoid arthritis using MRI scanning
1 Associate Professor in Rheumatology, Department of Molecular Medicine and Pathology, Faculty of Medicine and Health Sciences, University of Auckland, 85 Park Rd, Grafton, Auckland, New Zealand
2 Senior Lecturer in Rheumatology, Department of Medicine, Faculty of Medicine and Health Sciences, University of Auckland, 85 Park Rd, Grafton, Auckland, New Zealand
Arthritis Research & Therapy 2009, 11:124 doi:10.1186/ar2778
See related research by Munwiler et al., http://arthritis-research.com/content/11/3/R94Published: 14 September 2009
Predicting prognosis in the patient with newly diagnosed rheumatoid arthritis is of key importance so that high-cost therapies can be tailored to the needs of the individual. In a recent issue of Arthritis Research and Therapy, the prognostic significance of MRI changes at the forefoot has been studied. While progression to radiographic erosion occurred rarely in this group of patients exposed to potent disease-suppressing therapies, including TNF inhibitors, MRI bone edema, representing osteitis, has been further implicated as a forerunner to bone erosion. Early MRI scans of the forefoot were helpful in defining those with the potential to progress as well as those in a good prognosis category.