Table 1 |
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|
Demographic and clinical characteristics of rheumatoid arthritis patients treated with rituximab |
|
|
Age (years) |
62 (1.8) |
|
Female (%) |
61 |
|
Disease duration (years) |
15 (2.8) |
|
Previous therapies |
|
|
Number of disease-modifying anti-rheumatic drugs used |
2.6 (1 to 5) |
|
Number of biologic agents used |
1.6 (0 to 3) |
|
Baseline disease characteristics |
|
|
Rheumatoid factor-positive (%) |
52 |
|
Disease activity score of 28 joint counts |
6.3 (0.2) |
|
Swollen joints (28 joints) |
9.3 (1.1) |
|
Tender joints (28 joints) |
12.8 (1.3) |
|
Patient's pain assessment |
69.7 (2.9) |
|
Patient's global assessment |
67.3 (3.3) |
|
Physician's global assessment |
54.8 (3.4) |
|
Health Assessment Questionnaire |
0.9 (0.09) |
|
Erythrocyte sedimentation rate (mm/hour) |
51 (6.1) |
|
Hemoglobin (g/dl) |
12.9 (0.4) |
|
Concomitant disease-modifying anti-rheumatic drugs |
|
|
Methotrexate |
|
|
Patients (%) |
68 |
|
Dose (mg/week) |
16.3 (7.5 to 25) |
|
Leflunomide |
|
|
Patients (%) |
29 |
|
Dose (mg/day) |
17 (10 to 20) |
|
Glucocorticoids |
|
|
Patients (%) |
29 |
|
Dose (mg/day) |
5.5 (5 to 10) |
|
Rituximab monotherapy |
3 |
|
|
|
|
Data expressed as mean (standard error of the mean), percentage, or mean (range); n = 31. |
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|
Nakou et al. Arthritis Research & Therapy 2009 11:R131 doi:10.1186/ar2798 |
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