Figure 6.

Long-term changes in the immunoglobulin expression of B cells following rituximab treatment. Isolated bone marrow mononuclear cells were stained for immunoglobulin (Ig) expression comparing rituximab-naïve and treated patients. In (a) CD19⁺IgD⁺, (b) CD19⁺IgM⁺, (c) CD19⁺IgG⁺ and (d) CD19⁺IgA⁺ is shown. Box represents 25^th to 75^th percentile, line indicates median, whereas error bars represent range. Statistical evaluation was performed using the Mann-Whitney t-test.