Table 5

Odds ratios for having the metabolic syndrome in patients receiving methotrexate compared with those not on methotrexate

Odds ratio

95% confidence interval

P value

Crude

0.483

0.32 to 0.73

0.001

Model a

0.505

0.33 to 0.77

0.001

Model b

0.525

0.34 to 0.80

0.003

Model c

0.517

0.33 to 0.80

0.004

Crude = unadjusted model

Model a = adjusted for age and sex

Model b = adjusted for age, sex, disease duration, erythrocyte sedimentation rate and health assessment questionnaire score

Model c = adjusted for age, sex, disease duration, erythrocyte sedimentation rate, health assessment questionnaire score, sulphasalazine, hydroxyxhloroquine, leflunomide, anti-tumour necrosis factor therapy, glucocorticoid use and NSAID use.

Toms et al. Arthritis Research & Therapy 2009 11:R110   doi:10.1186/ar2765