Table 3

Characteristics of the patients with autoimmune thyroid diseases and skewed X-chromosome inactivation

Patient

Birth date

Disease onset

Pregnancy history

Diagnostic

Auto antibodies

90+% skewing

1

1978

22

G1, P1, A0

HT

+

2

1933

65

G11, P5, A0

HT

+

3

1969

20

G1, P1, A1

HT

+

4

1938

60

G3, P3, A0

GD

+

5

1943

45

G2, P2, A0

GD

+

6

1972

21

G2, P2, A0

HT

+

7

1964

36

G2, P2, A0

HT

+

8

1924

65

G9, P9, A0

HT

+

9

1940

59

G10, P10, A0

HT

+

10

1969

28

G4, P4, A0

GD

+

11

1979

20

G0, P0, A0

GD

-

12

1931

68

G13, P13, A0

HT

-

13

1943

59

G1, P1, A0

GD

-

14

1946

42

G2, P2, A0

GD

-

80 to 89% skewing

15

1969

23

G2, P2, A0

HT

+

16

1950

41

G3, P2, A1

GD

+

17

1980

20

G0, P0, A0

HT

+

18

1945

54

G4, P3, A0

HT

+

19

1962

36

G7, P2, A5

HT

+

20

1954

48

G3, P3, A0

GD

+

21

1984

20

G0, P0, A0

GD

+

22

1952

45

G2, P2, A0

GD

-

23

1941

58

G5, P5, A0

HT

-

24

1953

39

G2, P2, A0

GD

-

25

1947

48

G1, P1, A0

HT

-

26

1969

43

G2, P1, A1

GD

-

A = spontaneous abortions; G = number of pregnancies; GD = Graves' disease; HT = Hashimoto's thyroiditis; P = para (pregnancies carried to term and delivered).

Chabchoub et al. Arthritis Research & Therapy 2009 11:R106   doi:10.1186/ar2759