Table 6

Independent predictors of cortical hand bone loss, results from multivariate logistic regression analyses

One-year cortical hand bone loss

Two-year cortical hand bone loss

Five-year cortical hand bone loss

OR

(95% CI)

P value

OR

(95% CI)

P value

OR

(95% CI)

P value

Anti-CCP (> 25 U/ml)

2.2

(1.0 to 4.5)

0.04

2.6

(1.1 to 6.2)

0.03

4.9

(1.4 to 16.7)

0.01

ESR (> 20 mm/h)

4.5

(2.0 to 9.9)

< 0.001

3.5

(1.3 to 9.3)

0.01

Prednisolone use

4.7

(1.6 to 14.1)

0.006

Age (years)

1.0

(0.9 to 1.0)

0.62

1.0

(0.9 to 1.1)

0.23

1.1

(1.0 to 1.1)

0.89

Sex (female)

1.0

(0.4 to 2.4)

0.95

0.5

(0.2 to 1.3)

0.14

0.9

(0.2 to 3.4)

0.02

Constant

0.5

0.35

0.4

0.37

0.3

0.31

Final models after multivariate logistic regression analyses. Dependent variable: cortical hand bone loss (yes/no). Anti-CCP = antibodies to cyclic citrullinated peptide; CI = confidence interval; ESR = erythrocyte sedimentation rate; OR = odds ratio.

Bøyesen et al. Arthritis Research & Therapy 2009 11:R103   doi:10.1186/ar2749