Open Access Research article

Early and long-standing rheumatoid arthritis: distinct molecular signatures identified by gene-expression profiling in synovia

Thierry Lequerré1*, Carine Bansard2, Olivier Vittecoq1, Céline Derambure1, Martine Hiron2, Maryvonne Daveau2, François Tron2, Xavier Ayral3, Norman Biga4, Isabelle Auquit-Auckbur5, Gilles Chiocchia6, Xavier Le Loët1 and Jean-Philippe Salier2

Author Affiliations

1 Department of Rheumatology, Rouen University Hospital and Inserm 905 & Institut Fédératif de Recherche Multidisciplinaire sur les Peptides 23, Institute for Biomedical Research, University of Rouen, 76031 Rouen Cedex, and Consortium EGERIE, France

2 Inserm Unité 905, Institut Fédératif de Recherche Multidisciplinaire sur les Peptides 23, Institute for Biomedical Research, University of Rouen, Faculté de Médecine-Pharmacie, Rouen, France

3 Department of Rheumatology, Cochin Hospital, AP-HP, University of Paris-Descartes, 27, rue du faubourg Saint-Jacques, 75679 Paris Cedex 14, France

4 Department of Orthopedic and Traumatology, Rouen University Hospital, 76031 Rouen Cedex, France

5 Department of Plastic and Reconstructive Surgery, Rouen University Hospital, 76031 Rouen Cedex, France

6 Institut Cochin, Université Paris Descartes, Inserm (U567), CNRS (UMR8104), Paris, and Consortium EGERIE, France

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Arthritis Research & Therapy 2009, 11:R99  doi:10.1186/ar2744

Published: 29 June 2009

Additional files

Additional data file 1:

Word file containing a table with the baseline characteristics of controls and rheumatoid arthritis (RA) patients.

Format: DOC Size: 21KB Download file

This file can be viewed with: Microsoft Word Viewer

Open Data

Additional data file 2:

Adobe file containing a table listing the 719 genes differentially expressed at early RA versus long-standing RA.

Format: PDF Size: 138KB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data

Additional data file 3:

Word file containing a table listing the ontological classes of differentially expressed genes in early RA versus long-standing RA.

Format: DOC Size: 23KB Download file

This file can be viewed with: Microsoft Word Viewer

Open Data

Additional data file 4:

Adobe file containing a table listing the 116 genes differentially expressed at early RA versus controls.

Format: PDF Size: 16KB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data

Additional data file 5:

Adobe file containing a table listing the 52 genes differentially expressed at long-standing RA versus controls.

Format: PDF Size: 11KB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data