Arthritis Research & Therapy

official impact factor 4.36

Open Access Research article

Degradome expression profiling in human articular cartilage

Tracey E Swingler1, Jasmine G Waters1, Rosemary K Davidson1, Caroline J Pennington1, Xose S Puente2, Clare Darrah3, Adele Cooper3, Simon T Donell3, Geoffrey R Guile4, Wenjia Wang4 and Ian M Clark1*

Author Affiliations

1 School of Biological Sciences, University of East Anglia, Earlham Road, Norwich NR4 7TJ, UK

2 Departamento de Bioquímica y Biología Molecular, Facultad de Medicina, Universidad de Oviedo, 33006 Oviedo, Spain

3 Institute of Orthopaedics, Norfolk & Norwich University Hospital, Colney Lane, Norwich NR4 7UY, UK

4 School of Computing Sciences, University of East Anglia, Earlham Road, Norwich NR4 7TJ, UK

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Arthritis Research & Therapy 2009, 11:R96 doi:10.1186/ar2741

Published: 23 June 2009

Additional files

Additional data file 1:

Word file containing a table that lists full details of the LogitBoost-NR algorithms for gene selection and sample classification from gene expression data.

Format: DOC Size: 40KB Download file

This file can be viewed with: Microsoft Word Viewer

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Additional data file 2:

Excel file containing a spreadsheet of expression data for all protease genes assayed (median threshold cycle (Ct) of NOF and OA, fold difference and P values).

Format: XLS Size: 117KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data

Additional data file 3:

Excel file containing a spreadsheet of the rank order for all protease genes assayed by the LogitBoost-NR algorithm and the Wilcoxon test.

Format: XLS Size: 73KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data