Blood autoantibody and cytokine profiles predict response to anti-tumor necrosis factor therapy in rheumatoid arthritis

Wolfgang Hueber^1,2 , Beren H Tomooka^1,2 , Franak Batliwalla³ , Wentian Li³ , Paul A Monach^4,5 , Robert J Tibshirani⁶ , Ronald F Van Vollenhoven⁷ , Jon Lampa⁷ , Kazuyoshi Saito⁸ , Yoshiya Tanaka⁸ , Mark C Genovese¹ , Lars Klareskog⁷ , Peter K Gregersen³ and William H Robinson^1,2

¹  Department of Medicine, Division of Immunology & Rheumatology, Stanford University, 269 Campus Drive, mail code 5166, Stanford, CA 94305, USA

²  GRECC, VA Palo Alto Health Care Systems, 3801 Miranda Ave, mailstop 154R, Palo Alto, CA 94304, USA

³  Feinstein Institute of Medical Research, North Shore LIJ Health System, 350 Community Drive, Manhasset, NY 11030, USA

⁴  Joslin Diabetes Center, One Joslin Place, Boston, MA 02215, USA

⁵  Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115 USA

⁶  Department of Statistics, 390 Serra Mall, Stanford University, Stanford, CA 94305, USA

⁷  Karolinska Institutet, Building D2:02, SE-171 76 Stockholm, Sweden

⁸  First Department of Internal Medicine, University of Occupational & Environmental Health, 1-1 Iseigaoka, Yahata-nishi, Kitakyushu 807-8555, Japan