Table 2

Relationship between fatty acid intake and incidence of bone marrow lesions

Univariate analysis, OR (95% CI)

P value

Model 1

Multivariate analysis, OR (95% CI)^a

P value

Model 2

Multivariate analysis, OR (95% CI)^b

P value

Saturated fatty acids

1.08 (0.72–1.60)

0.73

2.62 (1.11–6.17)

0.03

2.56 (1.03–6.37)

0.04

Monounsaturated fatty acids

1.01 (0.66–1.52)

0.98

2.10 (0.81–5.47)

0.13

1.99 (0.75–5.31)

0.17

Polyunsaturated fatty acids

0.94 (0.62–1.42)

0.77

1.10 (0.64–1.90)

0.74

1.10 (0.62–1.96)

0.74

n-6 polyunsaturated fatty acids

0.88 (0.57–1.35)

0.55

0.98 (0.56–1.70)

0.93

0.98 (0.55–1.76)

0.96

n-3 polyunsaturated fatty acids

0.81 (0.53–1.25)

0.34

0.85 (0.46–1.56)

0.60

0.85 (0.45–1.61)

0.62

n-6/n-3 ratio

0.94 (0.63–1.38)

0.74

0.96 (0.65–1.41)

0.82

0.93 (0.61–1.42)

0.74

^aModel 1: odds ratio for development of tibiofemoral bone marrow lesions for each increase of 1 standard deviation in the respective fatty acid intake after adjusting for energy intake. ^bModel 2: odds ratio for development of tibiofemoral bone marrow lesions for each increase of 1 standard deviation in the respective fatty acid intake after adjusting for energy intake, age, gender, and body mass index. CI, confidence interval; OR, odds ratio.

Wang et al. Arthritis Research & Therapy 2009 11:R63   doi:10.1186/ar2688