Table 1

Comparison of rheumatoid arthritis patients and controls on pain and questionnaire responses

RA patients

(n = 19)

Controls

(n = 21)

P value


Responses to noxious stimuli

HPTh, °C

41.4 ± 5.1

44.4 ± 4.5

0.05

PPTh on leg, kPa

665.5 ± 287.7

811.3 ± 400.1

0.19

PPTh on thumb, kPa

295.7 ± 141.6

395.7 ± 150.7

0.03

PPTh on trapezius, kPa

404.5 ± 160.7

536.2 ± 276.9

0.08

Cold pain rating (0 to 100) at midpoint

82.3 ± 12.6

65.4 ± 25.6

0.01

Cold pain rating (0 to 100) at conclusion

83.0 ± 12.4

67.7 ± 24.8

0.02

Cold pain tolerance, seconds

61.8 ± 54.1

111.8 ± 63.8

0.01

Heat pain rating at 49°C

74.4 ± 25.1

57.7 ± 34.7

0.09

Heat pain rating at 51°C

86.8 ± 16.2

68.2 ± 32.4

0.03

Painful heat after-sensations

16.8 ± 23.2

5.7 ± 9.4

0.05

Questionnaire data

Current pain (0 to 10)

3.2 ± 2.3

0.4 ± 0.3

< 0.001

Current stress (0 to 10)

2.2 ± 2.4

1.2 ± 1.9

0.17

Beck Depression Inventory score

7.0 ± 6.3

2.5 ± 3.0

0.01

SF-36, subscale score

General health

52.9 ± 20.3

84.0 ± 19.4

< 0.001

Physical functioning

42.1 ± 24.2

69.1 ± 26.7

0.002

Physical role

28.9 ± 31.5

86.9 ± 28.1

< 0.001

Bodily pain

44.2 ± 21.3

85.7 ± 23.7

< 0.001

Energy/fatigue

53.4 ± 18.4

67.6 ± 18.1

0.02

Mental health

80.7 ± 13.7

81.0 ± 14.5

0.95

Emotional role

84.2 ± 34.0

93.7 ± 22.7

0.30

Social functioning

70.4 ± 27.7

94.6 ± 7.5

0.001


Data are presented as mean ± standard deviation. HPTh, heat pain threshold; PPTh, pressure pain threshold; RA, rheumatoid arthritis; SF-36, Short Form Health Survey-36.

Edwards et al. Arthritis Research & Therapy 2009 11:R61   doi:10.1186/ar2684

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