Table 1 |
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Examples of comorbid conditions by their relationship with rheumatoid arthritis |
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|
Estimated relationship to RA |
Comorbid condition |
Mechanism of relationship |
|
|
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|
High |
Anemia |
RA activity |
|
Osteoporosis |
CS, RA, decreased function |
|
|
Bacterial infection |
RA, CS, smoking, (TNF?) |
|
|
Medium |
Lymphoma |
RA activity, (TNF?) |
|
GI ulceration |
NSAIDs, CS |
|
|
Myocardial infarction |
RA, CS |
|
|
Heart failure |
RA, CS |
|
|
Low |
Stroke |
RA |
|
Depression |
Chronic pain |
|
|
Fracture |
CS, decreased function |
|
|
Skin cancer |
RA, TNF |
|
|
Any cancer |
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|
No relationship |
Appendicitis |
|
|
|
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|
CS, corticoid steroid treatment, GI, gastrointestinal; NSAID = Non-steroidal anti-inflammatory drug treatment; RA, rheumatoid arthritis; TNF, antitumor necrosis factor treatment. |
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|
Gabriel and Michaud Arthritis Research & Therapy 2009 11:229 doi:10.1186/ar2669 |
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