Arthritis Research & Therapy

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Developments in the scientific understanding of osteoarthritis

Steven B Abramson* and Mukundan Attur

Arthritis Research & Therapy 2009, 11:227 doi:10.1186/ar2655

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Celecoxib: considerations regarding its potential disease-modifying properties in osteoarthritis

Manon C Zweers, Tineke N de Boer, Joël van Roon, Johannes WJ Bijlsma, Floris PJG Lafeber, Simon C Mastbergen Arthritis Research & Therapy 2011, 13:239 (21 September 2011)

Research article   Open Access

Fibroblast growth factor receptor 1 is principally responsible for fibroblast growth factor 2-induced catabolic activities in human articular chondrocytes

Dongyao Yan, Di Chen, Simon M Cool, Andre J van Wijnen, Katalin Mikecz, Gillian Murphy, Hee-Jeong Im Arthritis Research & Therapy 2011, 13:R130 (11 August 2011)

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Comparison of glucose derivatives effects on cartilage degradation

Thanyaluck Phitak, Peraphan Pothacharoen, Prachya Kongtawelert BMC Musculoskeletal Disorders 2010, 11:162 (15 July 2010)

Glucosamine derivatives can alter anabolic and catabolic processes in human articular chondrocytes cultures and show chondroprotective effects, with glucosamine sulfate showing the highest chondroprotective activity in cartilage explants.

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Synergistic chondroprotective effects of curcumin and resveratrol in human articular chondrocytes: inhibition of IL-1β-induced NF-κB-mediated inflammation and apoptosis

Constanze Csaki, Ali Mobasheri, Mehdi Shakibaei Arthritis Research & Therapy 2009, 11:R165 (4 November 2009)