Table 2 |
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|
Univariate analysis of the relationship between change in flow-mediated dilatation and GTN-mediated dilatation, features of RA and CV risk factors in 31 patients with early RA |
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|
R2 |
β coeff |
P |
|
|
|
|||
|
FMD: |
|||
|
RF presence |
- |
- |
0.037 |
|
Log CRP level |
|||
|
At week 0 |
0.173 |
-0.946 |
0.020 |
|
At week 52 |
0.319 |
-1.700 |
0.001 |
|
ESR |
|||
|
At week 0 |
0.142 |
-1.451 |
0.037 |
|
At week 52 |
0.001 |
-0.065 |
0.91 |
|
Change in GMD |
0.428 |
0.487 |
< 0.001 |
|
Carotid IMT at baseline |
0.196 |
-10.22 |
0.013 |
|
Age |
0.346 |
-0.133 |
< 0.001 |
|
Post menopausal status |
- |
- |
0.002 |
|
GMD: |
|||
|
Log CRP level |
|||
|
At week 0 |
0.214 |
-0.394 |
0.006 |
|
At week 52 |
0.431 |
-0.693 |
< 0.001 |
|
Change in FMD |
0.428 |
0.880 |
< 0.001 |
|
Carotid IMT at baseline |
0.232 |
-3.89 |
0.007 |
|
Age |
0.206 |
-0.035 |
0.012 |
|
Pack year history |
0.173 |
-0.148 |
0.022 |
|
Ever smoking |
- |
- |
0.02 |
|
LDL |
|||
|
At week 0 |
0.173 |
-0.561 |
0.086 |
|
At week 52 |
0.352 |
-0.552 |
0.015 |
|
|
|||
|
Parameters showing statistically significant relationships are included. Bold values are statistically significant. CRP = C-reactive protein; CV = cardiovascular; ESR = erythrocyte sedimentation rate; FMD = flow-mediated dilatation; GMD = GTN-mediated dilatation; GTN = glyceryl trinitrate; IMT = intima-media thickening; LDL = low-density lipoprotein; RA = rheumatoid arthritis; RF = rheumatoid factor. |
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|
Hannawi et al. Arthritis Research & Therapy 2009 11:R51 doi:10.1186/ar2668 |
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