Table 4 |
|||
|
Allele frequency differences in tagSNPs of the intergenic 6q23 region: ACPA-positive cases versus controls |
|||
|
SNP |
MAF% (n/N) |
OR (95%CI) |
P |
|
|
|||
|
rs566097 |
|||
|
ACPA+ cases |
10.9 (84/772) |
0.94 (0.7 to 1.2) |
NS |
|
Controls |
11.5 (367/3,190) |
||
|
rs13207033 |
|||
|
ACPA+ cases |
25.1 (185/736) |
0.80 (0.66 to 0.96) |
0.015 |
|
Controls |
29.7 (914/3,082) |
||
|
rs489738 |
|||
|
ACPA+ cases |
18.2 (138/760) |
0.97 (0.8 to 1.2) |
NS |
|
Controls |
18.6 (586/3,158) |
||
|
rs12194935 |
|||
|
ACPA+ cases |
26.1 (198/758) |
1.18 (1.0 to 1.4) |
NS |
|
Controls |
23.0 (726/3,154) |
||
|
rs536331 |
|||
|
ACPA+ cases |
37.9 (292/770) |
0.83 (0.71 to 0.97) |
0.023 |
|
Controls |
42.4 (1,351/3,184) |
||
|
rs675520 |
|||
|
ACPA+ cases |
44.5 (334/750) |
0.82 (0.70 to 0.96) |
0.014 |
|
Controls |
49.5 (1,520/3,070) |
||
|
rs6920220 |
|||
|
ACPA+ cases |
22.3 (172/770) |
1.15 (0.95 to 1.39) |
NS |
|
Controls |
20.1 (639/3,184) |
||
|
rs694069 |
|||
|
ACPA+ cases |
35.5 (273/770) |
0.82 (0.70 to 0.97) |
0.019 |
|
Controls |
40.1 (1,276/3,186) |
||
|
rs6917441 |
|||
|
ACPA+ cases |
27.9 (212/760) |
1.11 (0.9 to 1.3) |
NS |
|
Controls |
25.8 (816/3,166) |
||
|
rs647108 |
|||
|
ACPA+ cases |
41.9 (321/766) |
1.04 (0.9 to 1.2) |
NS |
|
Controls |
41.0 (1,306/3,184) |
||
|
|
|||
|
Allele frequency differences in tag-single nucleotide polymorphism (SNP) of the intergenic 6q23 region between patients with rheumatoid arthritis positive for anti-citrullinated peptide antibodies (ACPA+ cases) and control individuals (controls). MAF, minor allele frequency; n, number of minor alleles; N, total number of alleles. |
|||
|
Dieguez-Gonzalez et al. Arthritis Research & Therapy 2009 11:R42 doi:10.1186/ar2650 |
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