Table 4 |
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|
Fatty acids in adipose tissue and serum levels of lipids and anti-PC IgM in women with rheumatoid arthritis (RA), separated for diet |
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|
Normal diet (n = 46) |
Mediterranean-like diet (n = 12) |
P value |
Mediterranean-like and vegetarian diets (n = 15) |
P value |
|
|
|
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|
Adipose tissue: |
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|
SFA |
29.2 (28.4 to 29.9) |
29.1 (27.5 to 30.7) |
0.60 |
28.8 (27.5 to 30.1) |
0.90 |
|
14:0 |
3.3 (3.1 to 3.5) |
3.4 (3.1 to 3.8) |
0.60 |
3.5 (3.2 to 3.8) |
0.43 |
|
16:0 |
21.7 (21.2 to 22.2) |
21.7 (20.4 to 23.1) |
0.92 |
21.4 (20.2 to 22.5) |
0.55 |
|
MUFA |
57.4 (56.7 to 58.1) |
56.1 (54.6 to 57.6) |
0.06 |
55.8 (54.4 to 57.2) |
0.016 |
|
16:1 n7 |
6.5 (6.0 to 6.9) |
6.0 (5.3 to 6.6) |
0.30 |
5.8 (5.2 to 6.4) |
0.13 |
|
18:1 n9 |
51.4 (50.9 to 52.0) |
50.2 (48.9 to 51.2) |
0.05 |
50.0 (49.0 to 51.0) |
0.019 |
|
Omega 3 |
1.8 (1.7 to 1.9) |
2.1 (1.7 to 2.6) |
0.039 |
2.2 (1.8 to 2.6) |
0.009 |
|
18:3 n3 |
1.1 (1.0 to 1.2) |
1.1 (0.93 to 1.2) |
0.72 |
1.1 (1.0 to 1.3) |
0.22 |
|
20:5 n3 |
0.14 (0.12 to 0.16) |
0.19 (0.12 to 0.25)* |
0.08 |
0.15 (0.11 to 0.25)* |
0.16 |
|
22:5 n3 |
0.33 (0.29 to 0.37) |
0.40 (0.31 to 0.50) |
0.06 |
0.39 (0.29 to 0.48) |
0.11 |
|
22:6 n3 |
0.32 (0.28 to 0.36) |
0.47 (0.25 to 0.59)* |
0.07 |
0.47 (0.20 to 0.60)* |
0.13 |
|
Omega 6 |
11.0 (10.6 to 11.3) |
12.0 (10.7 to 13.2) |
0.06 |
12.6 (11.2 to 14.1) |
0.004 |
|
18:2 n6 |
10.1 (9.7 to 10.5) |
11.2 (9.8 to 12.5) |
0.06 |
11.9 (10.4 to 13.4) |
0.003 |
|
20:4 n6 |
0.40 (0.36 to 0.44) |
0.39 (0.31 to 0.46) |
0.81 |
0.32 (0.26 to 0.45)* |
0.35 |
|
Serum lipids: |
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|
Cholesterol, mmol/l |
5.3 (5.0 to 5.6) |
5.1 (4.7 to 5.6) |
0.60 |
5.1 (4.8 to 5.5) |
0.57 |
|
HDL, mmol/l |
1.9 (1.7 to 2.0) |
1.9 (1.4 to 2.4) |
0.97 |
1.9 (1.5 to 2.3) |
0.86 |
|
LDL, mmol/l |
2.9 (2.7 to 3.2) |
2.8 (2.3 to 3.2) |
0.58 |
2.8 (2.3 to 3.2) |
0.52 |
|
OxLDL, U/l |
62.1 (55.7 to 68.4) |
59.4 (50.0 to 68.9) |
0.67 |
58.8 (51.2 to 66.3) |
0.57 |
|
Triacylglycerol, mmol/l |
0.98 (0.88 to 1.1) |
1.0 (0.82 to 1.2) |
0.63 |
1.0 (0.81 to 1.1) |
0.95 |
|
anti-PC IgM, U/mla |
43.5 (30.3 to 65.5) |
198.2 (171.6 to 209.2) |
<0.001 |
188.2 (63.3 to 208.1) |
<0.001 |
|
|
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|
Values are means (95% confidence interval) and amedians (interquartile range). The fatty acids in adipose tissue are expressed as a percentage of total fat. Significant results are in bold. Anti-PC IgM, antibodies against phosphorylcholine IgM; FA, fatty acid; HDL< high-density lipoprotein; LDL, low-density lipoprotein; MUFA, monounsaturated fatty acid; oxLDL, oxidized low-density lipoprotein; PUFA, polyunsaturated fatty acid; SFA, saturated fatty acid. |
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|
Elkan et al. Arthritis Research & Therapy 2009 11:R37 doi:10.1186/ar2643 |
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