Table 4

Relationship between adiposity measures and risk of primary knee and hip replacement

Primary knee replacement (n = 541)

Primary hip replacement (n = 468)

Heterogeneity of hazard ratios

Hazard ratio (95% confidence interval)

P value

Hazard ratio (95% confidence interval)

P value

(P value)

Weight (per 10 kg)

1.58 (1.51 to 1.65)

<0.001

1.22 (1.15 to 1.30)

<0.001

<0.0001

Body mass index (per 5 kg/m²)

1.88 (1.76 to 2.00)

<0.001

1.26 (1.15 to 1.38)

<0.001

<0.0001

Waist circumference (per 10 cm)

1.62 (1.53 to 1.72)

<0.001

1.10 (1.01 to 1.19)

0.03

<0.0001

Waist-to-hip ratio (per 0.1 unit)

1.43 (1.29 to 1.58)

<0.001

1.01 (0.85 to 1.19)

0.92

0.0004

Fat mass (per 10 kg)

1.88 (1.76 to 2.00)

<0.001

1.29 (1.18 to 1.41)

<0.001

<0.0001

Percentage fat (per 10%)

2.84 (2.47 to 3.26)

<0.001

1.37 (1.19 to 1.57)

<0.001

<0.0001

All models adjusted for age, country of birth, and highest level of education, stratifying by gender, representing an approximate change of one standard deviation for each of the adiposity measures.

Wang et al. Arthritis Research & Therapy 2009 11:R31   doi:10.1186/ar2636