Table 4

Effect size of allelic associations detectable in our study (100 cases and 100 matched controls)

Gene

SNP reference

Risk effect

Protective effect


TLR1

rs5743618

>1.80 (+13.4%)

<0.51 (-11.8%)

rs5743594

>2.03 (+11.4%)

<0.38 (-8.6%)

TLR2

rs3804099

>1.76 (+13.9%)

<0.56 (-13.8%)

rs4696480

>1.76 (+13.9%)

<0.56 (-13.8%)

TLR4

rs2737191

>1.78 (+13.7%)

<0.53 (-12.3%)

rs4986790

>2.85 (+8%)

<0.08 (-4.6%)

rs1554973

>1.86 (+12.8%)

<0.53 (-9.3%)

TLR6

rs5743810

>1.76 (+13.9%)

<0.56 (-13.7%)

TLR9

rs187084

>1.76 (+14%)

<0.55 (-13.2%)

rs352140

>1.76 (+13.9%)

<0.56 (-13.8%)


Effect sizes presented as allelic odds ratios (frequency differences between cases and controls) for the minor alleles.

Jaen et al. Arthritis Research & Therapy 2009 11:R5   doi:10.1186/ar2589

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