Table 3 |
|||||
|
Results of the genotype relative risk test in 100 French Caucasian families with rheumatoid arthritis |
|||||
|
Gene |
SNP reference |
Genotype |
Patients (n = 100) |
Controls (n = 100) |
P value |
|
|
|||||
|
TLR1 |
rs5743618 (+7765 S602I) |
GG |
52 |
49 |
0.67 |
|
GT |
44 |
44 |
|||
|
TT |
4 |
7 |
|||
|
rs5743594 (+3663) |
CC |
71 |
71 |
0.41 |
|
|
CT |
25 |
28 |
|||
|
TT |
4 |
1 |
|||
|
TLR2 |
rs3804099 (+15591 N199N) |
CC |
29 |
24 |
0.77 |
|
CT |
51 |
55 |
|||
|
TT |
20 |
21 |
|||
|
rs4696480 (-1938) |
TT |
18 |
21 |
0.89 |
|
|
TA |
56 |
53 |
|||
|
AA |
26 |
26 |
|||
|
TLR4 |
rs2737191 (-3869) |
AA |
46 |
47 |
0.29 |
|
AG |
44 |
41 |
|||
|
GG |
10 |
12 |
|||
|
rs4986790 (+8719 D259G) |
AA |
89 |
90 |
1 |
|
|
AG |
10 |
10 |
|||
|
GG |
1 |
0 |
|||
|
rs1554973 (+14229) |
TT |
56 |
58 |
0.88 |
|
|
TC |
39 |
36 |
|||
|
CC |
4 |
5 |
|||
|
TLR6 |
rs5743810 (+744 S249P) |
CC |
22 |
20 |
0.91 |
|
CT |
55 |
55 |
|||
|
TT |
23 |
25 |
|||
|
TLR9 |
rs187084 (+ 3483 P545P) |
CC |
18 |
16 |
0.89 |
|
CT |
45 |
48 |
|||
|
TT |
36 |
35 |
|||
|
rs352140 (-851) |
TT |
34 |
24 |
0.36 |
|
|
TC |
37 |
47 |
|||
|
CC |
28 |
28 |
|||
|
|
|||||
|
Jaen et al. Arthritis Research & Therapy 2009 11:R5 doi:10.1186/ar2589 |
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