Table 1

Comparison of SNPs in the present study with the literature (Reference SNP (rs) and PCR primers)

PubMed identifier

Gene

SNP reference

Allele

MAFa

Found in the literature?

PCR primers


Present study

TLR1

rs5743618

G/T

No

Forward, 5'-CCCGGAAAGTTATAGAGGAACCCT-3'

Reverse, 5'-TTCACCCAGAAAGAATCGTGCCCA-3'

Present study

rs5743594

C/T

No

Forward, 5'-AAGATCAGGGTGGTAGTGTTGG-3'

Reverse, 5'-CCCAATTCTTCCTCTCCAGCTT-3'

Present study

TLR2

rs3804099

C/T

No

Forward, 5'-ATCGTCTTCCTGGTTCAAGC-3'

Reverse, 5'-CAGTTCCAAACATTCCACGG-3'

Present study

rs4696480

T/A

No

Forward, 5'-CAAATTTAAAAGAGGGCAAGAAA-3'

Reverse, 5'-CAGTTTATTGTGAGAATGAGTTT-3'

Present study

TLR4

rs2737191

A/G

No

Forward, 5'-CATCCCCTACTTTCTTCACA-3'

Reverse, 5'-TCAACTCAGGACCCATAATC-3'

Present study

rs4986790

A/G

32%/32.50%

Yes: other name Asp299Gly

Forward, 5'-TCTGGGAGAATTTAGAAATGAA-3'

Reverse, 5'-AAACGTATCCAATGAAAAGAAG-3'

Present study

rs1554973

T/C

No

Forward, 5'-CAAAGGATATGTGAACAATAGG-3'

Reverse, 5'-AATCCCGTGAGTAGAGAATG-3'

Present study

TLR6

rs5743810

C/T

No

Forward, 5'-ACTTGGTTCGTGATATGTTCTA-3'

Reverse, 5'-AAACCCTTCACCTTGTTTTTCA-3'

Present study

TLR9

rs187084

C/T

No

Forward, 5'-TCTGGGACAAGTCCAGCCAG-3'

Reverse, 5'-GGACACTCCCAGCTCTGAAG-3'

Present study

rs352140

T/C

No

Forward, 5'-CTGCTAGCACACCGGATCAT-3'

Reverse, 5'-ATGATACCACCCAGAGTGGG-3'


aMutation allele frequency, presented as cases/controls.

Jaen et al. Arthritis Research & Therapy 2009 11:R5   doi:10.1186/ar2589

Open Data