Table 1 |
||||||
|
Comparison of SNPs in the present study with the literature (Reference SNP (rs) and PCR primers) |
||||||
|
PubMed identifier |
Gene |
SNP reference |
Allele |
MAFa |
Found in the literature? |
PCR primers |
|
|
||||||
|
Present study |
TLR1 |
rs5743618 |
G/T |
No |
Forward, 5'-CCCGGAAAGTTATAGAGGAACCCT-3' |
|
|
Reverse, 5'-TTCACCCAGAAAGAATCGTGCCCA-3' |
||||||
|
Present study |
rs5743594 |
C/T |
No |
Forward, 5'-AAGATCAGGGTGGTAGTGTTGG-3' |
||
|
Reverse, 5'-CCCAATTCTTCCTCTCCAGCTT-3' |
||||||
|
Present study |
TLR2 |
rs3804099 |
C/T |
No |
Forward, 5'-ATCGTCTTCCTGGTTCAAGC-3' |
|
|
Reverse, 5'-CAGTTCCAAACATTCCACGG-3' |
||||||
|
Present study |
rs4696480 |
T/A |
No |
Forward, 5'-CAAATTTAAAAGAGGGCAAGAAA-3' |
||
|
Reverse, 5'-CAGTTTATTGTGAGAATGAGTTT-3' |
||||||
|
Present study |
TLR4 |
rs2737191 |
A/G |
No |
Forward, 5'-CATCCCCTACTTTCTTCACA-3' |
|
|
Reverse, 5'-TCAACTCAGGACCCATAATC-3' |
||||||
|
Present study |
rs4986790 |
A/G |
32%/32.50% |
Yes: other name Asp299Gly |
Forward, 5'-TCTGGGAGAATTTAGAAATGAA-3' |
|
|
Reverse, 5'-AAACGTATCCAATGAAAAGAAG-3' |
||||||
|
Present study |
rs1554973 |
T/C |
No |
Forward, 5'-CAAAGGATATGTGAACAATAGG-3' |
||
|
Reverse, 5'-AATCCCGTGAGTAGAGAATG-3' |
||||||
|
Present study |
TLR6 |
rs5743810 |
C/T |
No |
Forward, 5'-ACTTGGTTCGTGATATGTTCTA-3' |
|
|
Reverse, 5'-AAACCCTTCACCTTGTTTTTCA-3' |
||||||
|
Present study |
TLR9 |
rs187084 |
C/T |
No |
Forward, 5'-TCTGGGACAAGTCCAGCCAG-3' |
|
|
Reverse, 5'-GGACACTCCCAGCTCTGAAG-3' |
||||||
|
Present study |
rs352140 |
T/C |
No |
Forward, 5'-CTGCTAGCACACCGGATCAT-3' |
||
|
Reverse, 5'-ATGATACCACCCAGAGTGGG-3' |
||||||
|
|
||||||
|
aMutation allele frequency, presented as cases/controls. |
||||||
|
Jaen et al. Arthritis Research & Therapy 2009 11:R5 doi:10.1186/ar2589 |
||||||
