Table 2

Identification of the increased neutrophil proteins by the treatment of granulocyte-macrophage colony-stimulating factor (GM-CSF)

m/z
Protein
Ratio (treated/untreated)
Fraction
Accession no. (Swiss-Prot)

2,176.0
S100 calcium binding protein A9
5.0
Cytosol
[Swiss-Prot:P06702]
763.4
Neuropeptide S
3.1
Cytosol
[Swiss-Prot:P0C0P6]
963.5
S100 calcium binding protein A8
2.9
Cytosol
[Swiss-Prot:P05109]
854.4
NADH dehydrogenase 1 α subcomplex subunit 3
2.7
Cytosol
[Swiss-Prot:O95167]
795.5
Membrane-associated guanylate kinase
2.7
Cytosol
[Swiss-Prot:Q96QZ7]
1,515.7
Actin, β
2.6
Cytosol
[Swiss-Prot:P60709]
825.2
Ubiquitin-conjugating enzyme E2 E1
7.8
Organelle/membrane
[Swiss-Prot:P51965]
1,791.0
Neutrophil gelatinase-associated lipocalin (NGAL)
4.0
Organelle/membrane
[Swiss-Prot:P80188]
841.2
BMP-binding endothelial regulator protein
3.7
Organelle/membrane
[Swiss-Prot:Q8N8U9]
845.2
Glycoprotein M6-b
3.0
Organelle/membrane
[Swiss-Prot:Q13491]
1,480.0
FYVE, RhoGEF and PH domain-containing protein 4
2.5
Organelle/membrane
[Swiss-Prot:Q96M96]

BMP, bone morphogenetic protein; FYVE, phenylalanine (F)/tyrosine (Y)/valine (V)/glutamic acid (E) domain; Rho, Ras homolog; GEF, guanine nucleotide exchange factor; PH, pleckstrin homology.

Katano et al. Arthritis Research & Therapy 2009 11:R3   doi:10.1186/ar2587

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