Table 2

Gastrointestinal risk of non-steroidal anti-inflammatory drugs/cyclooxygenase-2 from safest to riskiest

Nonacetylated salicylates (for example, salsalate)


Safer

Nabumetone

Celecoxib

Ibuprofen

Diclofenac

Sulindac

Naproxen

Indomethacin

Riskier

Ketoprofen


The table summarizes evidence from a series of studies [53-56].

Felson Arthritis Research & Therapy 2009 11:203   doi:10.1186/ar2531