Arthritis Research & Therapy | Volume 11 Issue 1

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	Volume 11 Issue 1
	Comment
	Editorial What do biomarkers tell us about the pathogenesis of ankylosing spondylitis? Walter P Maksymowych Arthritis Research & Therapy 2009, 11:101 (7 January 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Editorial Genetic control of disease in an experimental model for Sjögren's syndrome Åsa Andersson Arthritis Research & Therapy 2009, 11:102 (20 January 2009) Abstract \| Full text \| PDF \| PubMed
	Editorial Cyclophosphamide in systemic sclerosis: still in search of a 'real life' scenario Irene Miniati, Gabriele Valentini, Marco Cerinic Arthritis Research & Therapy 2009, 11:103 (23 January 2009) Abstract \| Full text \| PDF \| PubMed
	Editorial Innovative combination strategy to enhance effect and diminish adverse effects of glucocorticoids: another promise? Johannes WG Jacobs, Johannes WJ Bijlsma Arthritis Research & Therapy 2009, 11:105 (27 February 2009) Abstract \| Full text \| PDF \| PubMed
	Review
	Review Hypoxia. The role of hypoxia and HIF-dependent signalling events in rheumatoid arthritis Barbara Muz, Moddasar N Khan, Serafim Kiriakidis, Ewa M Paleolog Arthritis Research & Therapy 2009, 11:201 (20 January 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Antigen receptor signaling in the rheumatic diseases Julie Zikherman, Arthur Weiss Arthritis Research & Therapy 2009, 11:202 (30 January 2009) Abstract \| Full text \| PDF \| PubMed
	Review Developments in the clinical understanding of osteoarthritis David T Felson Arthritis Research & Therapy 2009, 11:203 (30 January 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Developments in the clinical understanding of rheumatoid arthritis Josef S Smolen, Daniel Aletaha Arthritis Research & Therapy 2009, 11:204 (30 January 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Randomized controlled trial design in rheumatoid arthritis: the past decade Vibeke Strand, Jeremy Sokolove Arthritis Research & Therapy 2009, 11:205 (30 January 2009) Abstract \| Full text \| PDF \| PubMed
	Review Garden of therapeutic delights: new targets in rheumatic diseases Jean M Waldburger, Gary S Firestein Arthritis Research & Therapy 2009, 11:206 (30 January 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Transcription profiling of rheumatic diseases Lisa GM van Baarsen, Carina L Bos, Tineke Pouw Kraan, Cornelis L Verweij Arthritis Research & Therapy 2009, 11:207 (30 January 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Developments in the scientific and clinical understanding of the spondyloarthritides Joachim Sieper Arthritis Research & Therapy 2009, 11:208 (30 January 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Gene therapy of the rheumatic diseases: 1998 to 2008 Christopher H Evans, Steven C Ghivizzani, Paul D Robbins Arthritis Research & Therapy 2009, 11:209 (30 January 2009) Abstract \| Full text \| PDF \| PubMed
	Review Osteoimmunology in rheumatic diseases Georg Schett Arthritis Research & Therapy 2009, 11:210 (30 January 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Tissue engineering in the rheumatic diseases Jochen Ringe, Michael Sittinger Arthritis Research & Therapy 2009, 11:211 (30 January 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Developments in the scientific and clinical understanding of autoinflammatory disorders Helen J Lachmann, Philip N Hawkins Arthritis Research & Therapy 2009, 11:212 (30 January 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Hypoxia. HIF-mediated articular chondrocyte function: prospects for cartilage repair Christopher L Murphy, Brendan L Thoms, Rasilaben J Vaghjiani, Jérôme E Lafont Arthritis Research & Therapy 2009, 11:213 (5 February 2009) Abstract \| Full text \| PDF \| PubMed
	Review Psoriatic arthritis: from pathogenesis to therapy Oliver FitzGerald, Robert Winchester Arthritis Research & Therapy 2009, 11:214 (12 February 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Hypoxia. Regulation of NFκB signalling during inflammation: the role of hydroxylases Kathryn M Oliver, Cormac T Taylor, Eoin P Cummins Arthritis Research & Therapy 2009, 11:215 (23 February 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Recent developments in anti-rheumatic drugs in pediatrics: treatment of juvenile idiopathic arthritis Kristen Hayward, Carol A Wallace Arthritis Research & Therapy 2009, 11:216 (23 February 2009) Abstract \| Full text \| PDF \| PubMed
	Report
	Correction Correction: What magnetic resonance imaging has told us about the pathogenesis of rheumatoid arthritis – the first 50 years Dennis McGonagle, Ai Tan Arthritis Research & Therapy 2009, 11:401 (22 January 2009) Full text \| PDF
	Correction Correction: Limited reliability of the indirect immunofluorescence technique for the detection of anti-Rib-P antibodies Michael Mahler, Jennifer T Ngo, Johannes Schulte-Pelkum, Tanja Luettich, Marvin J Fritzler Arthritis Research & Therapy 2009, 11:402 (26 January 2009) Full text \| PDF
	Announcement In memoriam: Professor Brian Maurice John Foxwell, 1956 to 2008 Fionula Brennan, Marc Feldmann Arthritis Research & Therapy 2009, 11:104 (27 February 2009) Full text \| PDF \| PubMed
	Research
	Research article Interactions among type I and type II interferon, tumor necrosis factor, and β-estradiol in the regulation of immune response-related gene expressions in systemic lupus erythematosus Hooi-Ming Lee, Toru Mima, Hidehiko Sugino, Chieko Aoki, Yasuo Adachi, Naoko Yoshio-Hoshino, Kenichi Matsubara, Norihiro Nishimoto Arthritis Research & Therapy 2009, 11:R1 (3 January 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article MRI bone oedema scores are higher in the arthritis mutilans form of psoriatic arthritis and correlate with high radiographic scores for joint damage Yu M Tan, Mikkel Østergaard, Anthony Doyle, Nicola Dalbeth, Maria Lobo, Quentin Reeves, Elizabeth Robinson, William J Taylor, Peter B Jones, Karen Pui, Jamie Lee, Fiona M McQueen Arthritis Research & Therapy 2009, 11:R2 (6 January 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000
	Research article Implication of granulocyte-macrophage colony-stimulating factor induced neutrophil gelatinase-associated lipocalin in pathogenesis of rheumatoid arthritis revealed by proteome analysis Masayoshi Katano, Kazuki Okamoto, Mitsumi Arito, Yuki Kawakami, Manae S Kurokawa, Naoya Suematsu, Sonoko Shimada, Hiroshi Nakamura, Yang Xiang, Kayo Masuko, Kusuki Nishioka, Kazuo Yudoh, Tomohiro Kato Arthritis Research & Therapy 2009, 11:R3 (8 January 2009) Abstract \| Full text \| PDF \| PubMed
	Research article The differential expressions of 78-kDa glucose-regulated protein of infiltrating plasma cells in peripheral joints with the histopathological variants of rheumatoid synovitis Weijia Dong, Xiaoyan Li, Yuan Feng, Chunmei Fan, Zhinan Chen, Ping Zhu Arthritis Research & Therapy 2009, 11:R4 (9 January 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article No evidence of major effects in several Toll-like receptor gene polymorphisms in rheumatoid arthritis Olivier Jaen, Elisabeth Petit-Teixeira, Holger Kirsten, Peter Ahnert, Luca Semerano, Céline Pierlot, Francois Cornelis, Marie-Christophe Boissier, Geraldine Falgarone, the European Consortium on Rheumatoid Arthritis Families Arthritis Research & Therapy 2009, 11:R5 (13 January 2009) Abstract \| Full text \| PDF
	Research article Increased expression of FcγRI/CD64 on circulating monocytes parallels ongoing inflammation and nephritis in lupus Yi Li, Pui Y Lee, Eric S Sobel, Sonali Narain, Minoru Satoh, Mark S Segal, Westley H Reeves, Hanno B Richards Arthritis Research & Therapy 2009, 11:R6 (14 January 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Women, men, and rheumatoid arthritis: analyses of disease activity, disease characteristics, and treatments in the QUEST-RA Study Tuulikki Sokka, Sergio Toloza, Maurizio Cutolo, Hannu Kautiainen, Heidi Makinen, Feride Gogus, Vlado Skakic, Humeira Badsha, Tõnu Peets, Asta Baranauskaite, Pál Géher, Ilona Újfalussy, Fotini N Skopouli, Maria Mavrommati, Rieke Alten, Christof Pohl, Jean Sibilia, Andrea Stancati, Fausto Salaffi, Wojciech Romanowski, Danuta Zarowny-Wierzbinska, Dan Henrohn, Barry Bresnihan, Patricia Minnock, Lene Knudsen, Johannes WG Jacobs, Jaime Calvo-Alen, Juris Lazovskis, Geraldo Pinheiro, Dmitry Karateev, Daina Andersone, Sylejman Rexhepi, Yusuf Yazici, Theodore Pincus, the QUEST-RA Group et al. Arthritis Research & Therapy 2009, 11:R7 (14 January 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Rheumatoid arthritis was more severe in women in an analysis of more than 6,000 patients, although the effects of gender on standard disease activity measures may explain the difference.
	Research article Egr-1 inhibits the expression of extracellular matrix genes in chondrocytes by TNFα-induced MEK/ERK signalling Jason S Rockel, Suzanne M Bernier, Andrew Leask Arthritis Research & Therapy 2009, 11:R8 (14 January 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article The response to oestrogen deprivation of the cartilage collagen degradation marker, CTX-II, is unique compared with other markers of collagen turnover Anne-Christine Bay-Jensen, Nadine CB Tabassi, Lene V Sondergaard, Thomas L Andersen, Frederik Dagnaes-Hansen, Patrick Garnero, Moustapha Kassem, Jean-Marie Delaissé Arthritis Research & Therapy 2009, 11:R9 (20 January 2009) Abstract \| Full text \| PDF \| PubMed
	Research article Dissection of a locus on mouse chromosome 5 reveals arthritis promoting and inhibitory genes Therese Lindvall, Jenny Karlsson, Rikard Holmdahl, Åsa Andersson Arthritis Research & Therapy 2009, 11:R10 (20 January 2009) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary A region of mouse chromosome 5 contains genes that control the incidence and severity of collagen-induced arthritis and serum levels of anti-collagen type II antibodies.
	Research article Bone marrow lesions from osteoarthritis knees are characterized by sclerotic bone that is less well mineralized David J Hunter, Lou Gerstenfeld, Gavin Bishop, A David Davis, Zach D Mason, Tom A Einhorn, Rose A Maciewicz, Pete Newham, Martyn Foster, Sonya Jackson, Elise F Morgan Arthritis Research & Therapy 2009, 11:R11 (26 January 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Bone marrow lesions adjacent to the subchondral plate in osteoarthritis patients awaiting a total knee replacement appear to be sclerotic, and have a lower mineral density than healthy bone.
	Research article Selective amplification of glucocorticoid anti-inflammatory activity through synergistic multi-target action of a combination drug Grant R Zimmermann, William Avery, Alyce L Finelli, Melissa Farwell, Christopher C Fraser, Alexis A Borisy Arthritis Research & Therapy 2009, 11:R12 (26 January 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Elevated expression of caspase-3 inhibitors, survivin and xIAP correlates with low levels of apoptosis in active rheumatoid synovium Anak ASSK Dharmapatni, Malcolm D Smith, David M Findlay, Christopher A Holding, Andreas Evdokiou, Michael J Ahern, Helen Weedon, Paul Chen, Gavin Screaton, Xiao N Xu, David R Haynes Arthritis Research & Therapy 2009, 11:R13 (27 January 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000
	Research article The retinoic acid binding protein CRABP2 is increased in murine models of degenerative joint disease Ian D Welch, Matthew F Cowan, Frank Beier, Tully M Underhill Arthritis Research & Therapy 2009, 11:R14 (28 January 2009) Abstract \| Full text \| PDF \| PubMed
	Research article Antirheumatic drug response signatures in human chondrocytes: potential molecular targets to stimulate cartilage regeneration Kristin Andreas, Thomas Häupl, Carsten Lübke, Jochen Ringe, Lars Morawietz, Anja Wachtel, Michael Sittinger, Christian Kaps Arthritis Research & Therapy 2009, 11:R15 (3 February 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Susceptibility of rheumatoid arthritis synovial fibroblasts to FasL- and TRAIL-induced apoptosis is cell cycle-dependent Noreen Pundt, Marvin A Peters, Christina Wunrau, Simon Strietholt, Carsten Fehrmann, Katja Neugebauer, Christine Seyfert, Frans van Valen, Thomas Pap, Ingmar Meinecke Arthritis Research & Therapy 2009, 11:R16 (5 February 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Distinct synovial immunopathology in Behçet disease and psoriatic arthritis Juan D Cañete, Raquel Celis, Troy Noordenbos, Conchita Moll, Jose A Gómez-Puerta, Pilar Pizcueta, Antonio Palacin, Paul P Tak, Raimon Sanmartí, Dominique Baeten Arthritis Research & Therapy 2009, 11:R17 (6 February 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Impaired vascular responses to parasympathetic nerve stimulation and muscarinic receptor activation in the submandibular gland in nonobese diabetic mice Ellen Berggreen, Krister Nyløkken, Nicolas Delaleu, Hamijeta Hajdaragic-Ibricevic, Malin V Jonsson Arthritis Research & Therapy 2009, 11:R18 (6 February 2009) Abstract \| Full text \| PDF \| PubMed
	Research article Heavy metal exposure reverses genetic resistance to Chlamydia-induced arthritis Robert D Inman, Basil Chiu Arthritis Research & Therapy 2009, 11:R19 (9 February 2009) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Resistance to Chlamydia-induced reactive arthritis in a rat model is dictated by genetically defined cytokine production in the joints controlling local pathogen clearance, and can be reversed by heavy metal exposure.
	Research article An in vitro study investigating the survival and phenotype of mesenchymal stem cells following injection into nucleus pulposus tissue Christine L Le Maitre, Pauline Baird, Anthony J Freemont, Judith A Hoyland Arthritis Research & Therapy 2009, 11:R20 (11 February 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Mesenchymal stem cells from older individuals differentiate into chondrocyte-like cells without additional stimulation in vitro, which could simplify strategies aimed at restoring disc extracellular matrix in patients with invertebral disc degeneration.
	Research article BALB/c mice genetically susceptible to proteoglycan-induced arthritis and spondylitis show colony-dependent differences in disease penetrance Balint Farkas, Ferenc Boldizsar, Oktavia Tarjanyi, Anna Laszlo, Simon M Lin, Gabor Hutas, Beata Tryniszewska, Aaron Mangold, Gyorgy Nagyeri, Holly L Rosenzweig, Alison Finnegan, Katalin Mikecz, Tibor T Glant Arthritis Research & Therapy 2009, 11:R21 (16 February 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Antibodies against PM/Scl-75 and PM/Scl-100 are independent markers for different subsets of systemic sclerosis patients Katharina Hanke, Claudia S Brückner, Cornelia Dähnrich, Dörte Huscher, Lars Komorowski, Wolfgang Meyer, Anthonia Janssen, Marina Backhaus, Mike Becker, Angela Kill, Karl Egerer, Gerd R Burmester, Falk Hiepe, Wolfgang Schlumberger, Gabriela Riemekasten Arthritis Research & Therapy 2009, 11:R22 (16 February 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article The proliferative human monocyte subpopulation contains osteoclast precursors Roya Lari, Peter D Kitchener, John A Hamilton Arthritis Research & Therapy 2009, 11:R23 (17 February 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000
	Research article Blockade of lymphotoxin-beta receptor signaling reduces aspects of Sjögren's syndrome in salivary glands of non-obese diabetic mice Margaret K Gatumu, Kathrine Skarstein, Adrian Papandile, Jeffrey L Browning, Roy A Fava, Anne Bolstad Arthritis Research & Therapy 2009, 11:R24 (18 February 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article In vitro model for the analysis of synovial fibroblast-mediated degradation of intact cartilage David Pretzel, Dirk Pohlers, Sönke Weinert, Raimund W Kinne Arthritis Research & Therapy 2009, 11:R25 (18 February 2009) Abstract \| Full text \| PDF \| PubMed \| F1000
	Research article Medication persistence over 2 years of follow-up in a cohort of early rheumatoid arthritis patients: associated factors and relationship with disease activity and with disability Virginia Pascual-Ramos, Irazú Contreras-Yáñez, Antonio R Villa, Javier Cabiedes, Marina Rull-Gabayet Arthritis Research & Therapy 2009, 11:R26 (19 February 2009) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Younger early rheumatoid arthritis patients are more persistent with medication than their older counterparts, meaning they reach sustained remission more quickly and benefit from reduced disease activity and disability levels.
	Research article Reduced IgG anti-small nuclear ribonucleoprotein autoantibody production in systemic lupus erythematosus patients with positive IgM anti-cytomegalovirus antibodies Claudia Palafox Sánchez, Minoru Satoh, Edward KL Chan, Wendy C Carcamo, José Muñoz Valle, Gerardo Orozco Barocio, Edith Oregon Romero, Rosa Navarro Hernández, Mario Salazar Páramo, Antonio Cabral Castañeda, Mónica Vázquez del Mercado Arthritis Research & Therapy 2009, 11:R27 (20 February 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Diagnostic value of anti-topoisomerase I antibodies in a large monocentric cohort Katharina Hanke, Cornelia Dähnrich, Claudia S Brückner, Dörte Huscher, Mike Becker, Anthonina Jansen, Wolfgang Meyer, Karl Egerer, Falk Hiepe, Gerd R Burmester, Wolfgang Schlumberger, Gabriela Riemekasten Arthritis Research & Therapy 2009, 11:R28 (21 February 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Detection of anti-topoisomerase I autoantibody by immunoassays correlates with severity of fibrotic manifestations, disease activity and prognosis, according to an analysis of sera from 280 systemic sclerosis patients.
	Research article Cardiovascular risk factors and acute-phase response in idiopathic ascending aortitis: a case control study Vaidehi R Chowdhary, Cynthia S Crowson, Kimberly P Liang, Clement J Michet, Dylan V Miller, Kenneth J Warrington, Eric L Matteson Arthritis Research & Therapy 2009, 11:R29 (27 February 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central

	Volume 11 Issue 1
	Comment
	Editorial What do biomarkers tell us about the pathogenesis of ankylosing spondylitis? Walter P Maksymowych Arthritis Research & Therapy 2009, 11:101 (7 January 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Editorial Genetic control of disease in an experimental model for Sjögren's syndrome Åsa Andersson Arthritis Research & Therapy 2009, 11:102 (20 January 2009) Abstract \| Full text \| PDF \| PubMed
	Editorial Cyclophosphamide in systemic sclerosis: still in search of a 'real life' scenario Irene Miniati, Gabriele Valentini, Marco Cerinic Arthritis Research & Therapy 2009, 11:103 (23 January 2009) Abstract \| Full text \| PDF \| PubMed
	Editorial Innovative combination strategy to enhance effect and diminish adverse effects of glucocorticoids: another promise? Johannes WG Jacobs, Johannes WJ Bijlsma Arthritis Research & Therapy 2009, 11:105 (27 February 2009) Abstract \| Full text \| PDF \| PubMed
	Review
	Review Hypoxia. The role of hypoxia and HIF-dependent signalling events in rheumatoid arthritis Barbara Muz, Moddasar N Khan, Serafim Kiriakidis, Ewa M Paleolog Arthritis Research & Therapy 2009, 11:201 (20 January 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Antigen receptor signaling in the rheumatic diseases Julie Zikherman, Arthur Weiss Arthritis Research & Therapy 2009, 11:202 (30 January 2009) Abstract \| Full text \| PDF \| PubMed
	Review Developments in the clinical understanding of osteoarthritis David T Felson Arthritis Research & Therapy 2009, 11:203 (30 January 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Developments in the clinical understanding of rheumatoid arthritis Josef S Smolen, Daniel Aletaha Arthritis Research & Therapy 2009, 11:204 (30 January 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Randomized controlled trial design in rheumatoid arthritis: the past decade Vibeke Strand, Jeremy Sokolove Arthritis Research & Therapy 2009, 11:205 (30 January 2009) Abstract \| Full text \| PDF \| PubMed
	Review Garden of therapeutic delights: new targets in rheumatic diseases Jean M Waldburger, Gary S Firestein Arthritis Research & Therapy 2009, 11:206 (30 January 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Transcription profiling of rheumatic diseases Lisa GM van Baarsen, Carina L Bos, Tineke Pouw Kraan, Cornelis L Verweij Arthritis Research & Therapy 2009, 11:207 (30 January 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Developments in the scientific and clinical understanding of the spondyloarthritides Joachim Sieper Arthritis Research & Therapy 2009, 11:208 (30 January 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Gene therapy of the rheumatic diseases: 1998 to 2008 Christopher H Evans, Steven C Ghivizzani, Paul D Robbins Arthritis Research & Therapy 2009, 11:209 (30 January 2009) Abstract \| Full text \| PDF \| PubMed
	Review Osteoimmunology in rheumatic diseases Georg Schett Arthritis Research & Therapy 2009, 11:210 (30 January 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Tissue engineering in the rheumatic diseases Jochen Ringe, Michael Sittinger Arthritis Research & Therapy 2009, 11:211 (30 January 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Developments in the scientific and clinical understanding of autoinflammatory disorders Helen J Lachmann, Philip N Hawkins Arthritis Research & Therapy 2009, 11:212 (30 January 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Hypoxia. HIF-mediated articular chondrocyte function: prospects for cartilage repair Christopher L Murphy, Brendan L Thoms, Rasilaben J Vaghjiani, Jérôme E Lafont Arthritis Research & Therapy 2009, 11:213 (5 February 2009) Abstract \| Full text \| PDF \| PubMed
	Review Psoriatic arthritis: from pathogenesis to therapy Oliver FitzGerald, Robert Winchester Arthritis Research & Therapy 2009, 11:214 (12 February 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Hypoxia. Regulation of NFκB signalling during inflammation: the role of hydroxylases Kathryn M Oliver, Cormac T Taylor, Eoin P Cummins Arthritis Research & Therapy 2009, 11:215 (23 February 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Recent developments in anti-rheumatic drugs in pediatrics: treatment of juvenile idiopathic arthritis Kristen Hayward, Carol A Wallace Arthritis Research & Therapy 2009, 11:216 (23 February 2009) Abstract \| Full text \| PDF \| PubMed
	Report
	Correction Correction: What magnetic resonance imaging has told us about the pathogenesis of rheumatoid arthritis – the first 50 years Dennis McGonagle, Ai Tan Arthritis Research & Therapy 2009, 11:401 (22 January 2009) Full text \| PDF
	Correction Correction: Limited reliability of the indirect immunofluorescence technique for the detection of anti-Rib-P antibodies Michael Mahler, Jennifer T Ngo, Johannes Schulte-Pelkum, Tanja Luettich, Marvin J Fritzler Arthritis Research & Therapy 2009, 11:402 (26 January 2009) Full text \| PDF
	Announcement In memoriam: Professor Brian Maurice John Foxwell, 1956 to 2008 Fionula Brennan, Marc Feldmann Arthritis Research & Therapy 2009, 11:104 (27 February 2009) Full text \| PDF \| PubMed
	Research
	Research article Interactions among type I and type II interferon, tumor necrosis factor, and β-estradiol in the regulation of immune response-related gene expressions in systemic lupus erythematosus Hooi-Ming Lee, Toru Mima, Hidehiko Sugino, Chieko Aoki, Yasuo Adachi, Naoko Yoshio-Hoshino, Kenichi Matsubara, Norihiro Nishimoto Arthritis Research & Therapy 2009, 11:R1 (3 January 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article MRI bone oedema scores are higher in the arthritis mutilans form of psoriatic arthritis and correlate with high radiographic scores for joint damage Yu M Tan, Mikkel Østergaard, Anthony Doyle, Nicola Dalbeth, Maria Lobo, Quentin Reeves, Elizabeth Robinson, William J Taylor, Peter B Jones, Karen Pui, Jamie Lee, Fiona M McQueen Arthritis Research & Therapy 2009, 11:R2 (6 January 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000
	Research article Implication of granulocyte-macrophage colony-stimulating factor induced neutrophil gelatinase-associated lipocalin in pathogenesis of rheumatoid arthritis revealed by proteome analysis Masayoshi Katano, Kazuki Okamoto, Mitsumi Arito, Yuki Kawakami, Manae S Kurokawa, Naoya Suematsu, Sonoko Shimada, Hiroshi Nakamura, Yang Xiang, Kayo Masuko, Kusuki Nishioka, Kazuo Yudoh, Tomohiro Kato Arthritis Research & Therapy 2009, 11:R3 (8 January 2009) Abstract \| Full text \| PDF \| PubMed
	Research article The differential expressions of 78-kDa glucose-regulated protein of infiltrating plasma cells in peripheral joints with the histopathological variants of rheumatoid synovitis Weijia Dong, Xiaoyan Li, Yuan Feng, Chunmei Fan, Zhinan Chen, Ping Zhu Arthritis Research & Therapy 2009, 11:R4 (9 January 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article No evidence of major effects in several Toll-like receptor gene polymorphisms in rheumatoid arthritis Olivier Jaen, Elisabeth Petit-Teixeira, Holger Kirsten, Peter Ahnert, Luca Semerano, Céline Pierlot, Francois Cornelis, Marie-Christophe Boissier, Geraldine Falgarone, the European Consortium on Rheumatoid Arthritis Families Arthritis Research & Therapy 2009, 11:R5 (13 January 2009) Abstract \| Full text \| PDF
	Research article Increased expression of FcγRI/CD64 on circulating monocytes parallels ongoing inflammation and nephritis in lupus Yi Li, Pui Y Lee, Eric S Sobel, Sonali Narain, Minoru Satoh, Mark S Segal, Westley H Reeves, Hanno B Richards Arthritis Research & Therapy 2009, 11:R6 (14 January 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Women, men, and rheumatoid arthritis: analyses of disease activity, disease characteristics, and treatments in the QUEST-RA Study Tuulikki Sokka, Sergio Toloza, Maurizio Cutolo, Hannu Kautiainen, Heidi Makinen, Feride Gogus, Vlado Skakic, Humeira Badsha, Tõnu Peets, Asta Baranauskaite, Pál Géher, Ilona Újfalussy, Fotini N Skopouli, Maria Mavrommati, Rieke Alten, Christof Pohl, Jean Sibilia, Andrea Stancati, Fausto Salaffi, Wojciech Romanowski, Danuta Zarowny-Wierzbinska, Dan Henrohn, Barry Bresnihan, Patricia Minnock, Lene Knudsen, Johannes WG Jacobs, Jaime Calvo-Alen, Juris Lazovskis, Geraldo Pinheiro, Dmitry Karateev, Daina Andersone, Sylejman Rexhepi, Yusuf Yazici, Theodore Pincus, the QUEST-RA Group et al. Arthritis Research & Therapy 2009, 11:R7 (14 January 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Rheumatoid arthritis was more severe in women in an analysis of more than 6,000 patients, although the effects of gender on standard disease activity measures may explain the difference.
	Research article Egr-1 inhibits the expression of extracellular matrix genes in chondrocytes by TNFα-induced MEK/ERK signalling Jason S Rockel, Suzanne M Bernier, Andrew Leask Arthritis Research & Therapy 2009, 11:R8 (14 January 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article The response to oestrogen deprivation of the cartilage collagen degradation marker, CTX-II, is unique compared with other markers of collagen turnover Anne-Christine Bay-Jensen, Nadine CB Tabassi, Lene V Sondergaard, Thomas L Andersen, Frederik Dagnaes-Hansen, Patrick Garnero, Moustapha Kassem, Jean-Marie Delaissé Arthritis Research & Therapy 2009, 11:R9 (20 January 2009) Abstract \| Full text \| PDF \| PubMed
	Research article Dissection of a locus on mouse chromosome 5 reveals arthritis promoting and inhibitory genes Therese Lindvall, Jenny Karlsson, Rikard Holmdahl, Åsa Andersson Arthritis Research & Therapy 2009, 11:R10 (20 January 2009) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary A region of mouse chromosome 5 contains genes that control the incidence and severity of collagen-induced arthritis and serum levels of anti-collagen type II antibodies.
	Research article Bone marrow lesions from osteoarthritis knees are characterized by sclerotic bone that is less well mineralized David J Hunter, Lou Gerstenfeld, Gavin Bishop, A David Davis, Zach D Mason, Tom A Einhorn, Rose A Maciewicz, Pete Newham, Martyn Foster, Sonya Jackson, Elise F Morgan Arthritis Research & Therapy 2009, 11:R11 (26 January 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Bone marrow lesions adjacent to the subchondral plate in osteoarthritis patients awaiting a total knee replacement appear to be sclerotic, and have a lower mineral density than healthy bone.
	Research article Selective amplification of glucocorticoid anti-inflammatory activity through synergistic multi-target action of a combination drug Grant R Zimmermann, William Avery, Alyce L Finelli, Melissa Farwell, Christopher C Fraser, Alexis A Borisy Arthritis Research & Therapy 2009, 11:R12 (26 January 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Elevated expression of caspase-3 inhibitors, survivin and xIAP correlates with low levels of apoptosis in active rheumatoid synovium Anak ASSK Dharmapatni, Malcolm D Smith, David M Findlay, Christopher A Holding, Andreas Evdokiou, Michael J Ahern, Helen Weedon, Paul Chen, Gavin Screaton, Xiao N Xu, David R Haynes Arthritis Research & Therapy 2009, 11:R13 (27 January 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000
	Research article The retinoic acid binding protein CRABP2 is increased in murine models of degenerative joint disease Ian D Welch, Matthew F Cowan, Frank Beier, Tully M Underhill Arthritis Research & Therapy 2009, 11:R14 (28 January 2009) Abstract \| Full text \| PDF \| PubMed
	Research article Antirheumatic drug response signatures in human chondrocytes: potential molecular targets to stimulate cartilage regeneration Kristin Andreas, Thomas Häupl, Carsten Lübke, Jochen Ringe, Lars Morawietz, Anja Wachtel, Michael Sittinger, Christian Kaps Arthritis Research & Therapy 2009, 11:R15 (3 February 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Susceptibility of rheumatoid arthritis synovial fibroblasts to FasL- and TRAIL-induced apoptosis is cell cycle-dependent Noreen Pundt, Marvin A Peters, Christina Wunrau, Simon Strietholt, Carsten Fehrmann, Katja Neugebauer, Christine Seyfert, Frans van Valen, Thomas Pap, Ingmar Meinecke Arthritis Research & Therapy 2009, 11:R16 (5 February 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Distinct synovial immunopathology in Behçet disease and psoriatic arthritis Juan D Cañete, Raquel Celis, Troy Noordenbos, Conchita Moll, Jose A Gómez-Puerta, Pilar Pizcueta, Antonio Palacin, Paul P Tak, Raimon Sanmartí, Dominique Baeten Arthritis Research & Therapy 2009, 11:R17 (6 February 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Impaired vascular responses to parasympathetic nerve stimulation and muscarinic receptor activation in the submandibular gland in nonobese diabetic mice Ellen Berggreen, Krister Nyløkken, Nicolas Delaleu, Hamijeta Hajdaragic-Ibricevic, Malin V Jonsson Arthritis Research & Therapy 2009, 11:R18 (6 February 2009) Abstract \| Full text \| PDF \| PubMed
	Research article Heavy metal exposure reverses genetic resistance to Chlamydia-induced arthritis Robert D Inman, Basil Chiu Arthritis Research & Therapy 2009, 11:R19 (9 February 2009) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Resistance to Chlamydia-induced reactive arthritis in a rat model is dictated by genetically defined cytokine production in the joints controlling local pathogen clearance, and can be reversed by heavy metal exposure.
	Research article An in vitro study investigating the survival and phenotype of mesenchymal stem cells following injection into nucleus pulposus tissue Christine L Le Maitre, Pauline Baird, Anthony J Freemont, Judith A Hoyland Arthritis Research & Therapy 2009, 11:R20 (11 February 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Mesenchymal stem cells from older individuals differentiate into chondrocyte-like cells without additional stimulation in vitro, which could simplify strategies aimed at restoring disc extracellular matrix in patients with invertebral disc degeneration.
	Research article BALB/c mice genetically susceptible to proteoglycan-induced arthritis and spondylitis show colony-dependent differences in disease penetrance Balint Farkas, Ferenc Boldizsar, Oktavia Tarjanyi, Anna Laszlo, Simon M Lin, Gabor Hutas, Beata Tryniszewska, Aaron Mangold, Gyorgy Nagyeri, Holly L Rosenzweig, Alison Finnegan, Katalin Mikecz, Tibor T Glant Arthritis Research & Therapy 2009, 11:R21 (16 February 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Antibodies against PM/Scl-75 and PM/Scl-100 are independent markers for different subsets of systemic sclerosis patients Katharina Hanke, Claudia S Brückner, Cornelia Dähnrich, Dörte Huscher, Lars Komorowski, Wolfgang Meyer, Anthonia Janssen, Marina Backhaus, Mike Becker, Angela Kill, Karl Egerer, Gerd R Burmester, Falk Hiepe, Wolfgang Schlumberger, Gabriela Riemekasten Arthritis Research & Therapy 2009, 11:R22 (16 February 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article The proliferative human monocyte subpopulation contains osteoclast precursors Roya Lari, Peter D Kitchener, John A Hamilton Arthritis Research & Therapy 2009, 11:R23 (17 February 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000
	Research article Blockade of lymphotoxin-beta receptor signaling reduces aspects of Sjögren's syndrome in salivary glands of non-obese diabetic mice Margaret K Gatumu, Kathrine Skarstein, Adrian Papandile, Jeffrey L Browning, Roy A Fava, Anne Bolstad Arthritis Research & Therapy 2009, 11:R24 (18 February 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article In vitro model for the analysis of synovial fibroblast-mediated degradation of intact cartilage David Pretzel, Dirk Pohlers, Sönke Weinert, Raimund W Kinne Arthritis Research & Therapy 2009, 11:R25 (18 February 2009) Abstract \| Full text \| PDF \| PubMed \| F1000
	Research article Medication persistence over 2 years of follow-up in a cohort of early rheumatoid arthritis patients: associated factors and relationship with disease activity and with disability Virginia Pascual-Ramos, Irazú Contreras-Yáñez, Antonio R Villa, Javier Cabiedes, Marina Rull-Gabayet Arthritis Research & Therapy 2009, 11:R26 (19 February 2009) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Younger early rheumatoid arthritis patients are more persistent with medication than their older counterparts, meaning they reach sustained remission more quickly and benefit from reduced disease activity and disability levels.
	Research article Reduced IgG anti-small nuclear ribonucleoprotein autoantibody production in systemic lupus erythematosus patients with positive IgM anti-cytomegalovirus antibodies Claudia Palafox Sánchez, Minoru Satoh, Edward KL Chan, Wendy C Carcamo, José Muñoz Valle, Gerardo Orozco Barocio, Edith Oregon Romero, Rosa Navarro Hernández, Mario Salazar Páramo, Antonio Cabral Castañeda, Mónica Vázquez del Mercado Arthritis Research & Therapy 2009, 11:R27 (20 February 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Diagnostic value of anti-topoisomerase I antibodies in a large monocentric cohort Katharina Hanke, Cornelia Dähnrich, Claudia S Brückner, Dörte Huscher, Mike Becker, Anthonina Jansen, Wolfgang Meyer, Karl Egerer, Falk Hiepe, Gerd R Burmester, Wolfgang Schlumberger, Gabriela Riemekasten Arthritis Research & Therapy 2009, 11:R28 (21 February 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Detection of anti-topoisomerase I autoantibody by immunoassays correlates with severity of fibrotic manifestations, disease activity and prognosis, according to an analysis of sera from 280 systemic sclerosis patients.
	Research article Cardiovascular risk factors and acute-phase response in idiopathic ascending aortitis: a case control study Vaidehi R Chowdhary, Cynthia S Crowson, Kimberly P Liang, Clement J Michet, Dylan V Miller, Kenneth J Warrington, Eric L Matteson Arthritis Research & Therapy 2009, 11:R29 (27 February 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central

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