Vascular endothelial mediators and their effects. Adapted with permission from Lüscher and Barton . Ang, angiotensin; bFGF, basic fibroblast growth factor; ET, endothelin; ETA/B, endothelin receptor subtype A/B; ICAM, intracytoplasmic adhesion molecule; IL, interleukin; LDL, low-density lipoprotein; oxLDL, oxidized low-density lipoprotein; MCP, monocyte chemoattractant protein; NO, nitric oxide; NOS, nitric oxide synthase; O2-, superoxide; ONOO-, peroxynitrite; PAI, plasminogen activator inhibitor; PDGF, platelet derived growth factor; TGF, transforming growth factor; TNF, tumor necrosis factor; VCAM, vascular cell adhesion molecule.
Mackenzie et al. Arthritis Research & Therapy 2008 10(Suppl 2):S3 doi:10.1186/ar2464