Figure 1.
Therapeutic potential of exogenous nitric oxide (NO) in NSAID-induced gastric damage.
Presented is a diagram of the pathogenesis of NSAID-induced gastric mucosal injury
and the possible steps at which exogenous NO could help to protect against NSAID-induced
gastric damage. Reproduced with permission from Wallace [53]. COX, cyclo-oxygenase; NSAID, nonsteroidal anti-inflammatory drug.
Berenbaum Arthritis Research & Therapy 2008 10(Suppl 2):S1 doi:10.1186/ar2462 |