Table 3

Comparison of the number of serious NSAID ulcer complications and associated costs in the two extrapolations (all using PPIs vs none using PPIs)


No PPI users
(n = 1,000)
PPI users
(n = 1,000)
Difference

No. of complications (95% CI)
13.8 (13.7 to 13.9)
3.60 (3.56 to 3.64)
10.2
Costsa (95% CI)
€ 115,676 (114,874 to 116,493)
€ 165,770 (160,789 to 173,444)
€ 50,094

aCost of cheapest concomitant PPI (generic omeprazole) was taken into account. NSAID, non-steroidal anti-inflammatory drug; PPI, proton pump inhibitor.

Vonkeman et al. Arthritis Research & Therapy 2008 10:R144   doi:10.1186/ar2577

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