Figure 3.

Treatment effects over time on disease activity, function and disease progression. Effect over time of different treatments on disease activity score from 28-joint count with three parameters (DAS28-3), function (Health Assessment Questionnaire (HAQ)), and disease progression (Larsen score). Pikes and lines represent the estimated β coefficients and 95% confidence intervals in the weighted estimating equations, adjusted by covariates and calendar year (see Statistical analysis). *P < 0.05, **P < 0.01.